Changes in bacterial flora of nose and throat before and after antibiotic therapy for acne
Not Applicable
- Conditions
- Health Condition 1: L700- Acne vulgaris
- Registration Number
- CTRI/2019/11/021864
- Lead Sponsor
- GCS Medical college Hospital and Research center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients greater than 14 years of age
Patients clinically diagnosed as moderate to severe acne requiring oral antibiotics at the discretion of PI
Exclusion Criteria
Patients lesser than 14 years of age
Patients with concomitant systemic illness
Patients with history of prior antibiotic therapy for acne or other illness in the last 3 months
ï?· Patients in a health care related occupation
ï?· Pregnant or lactating patients
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. to study the colonisation status of Staphylococcus aureus in anterior nose and Streptococcus pyogenes <br/ ><br>in oropharynx before and after oral antibiotics in acne patients <br/ ><br>2. to study the antibiotic resistance patterns of Staphylococcus aureus in anterior nose and Streptococcus <br/ ><br>pyogenes in oropharynx before and after oral antibiotics in acne patientsTimepoint: End of duration of oral antibiotics on discretion of PI. There is no consensus on duration of oral antibiotic therapy and may extend from a period of 15 days to 6 months.
- Secondary Outcome Measures
Name Time Method To study the correlation of colonisation and sensitivity patterns of proposed research bacteria in <br/ ><br>proposed body sites with type of antibiotic and duration of antibiotic use.Timepoint: End of duration of oral antibiotics on discretion of PI. There is no consensus on duration of oral antibiotic therapy and may extend from a period of 15 days to 6 months.