A research study for treatment of mild to moderate ulcerative colitis with ayurvedic drugs and comparison with Allopathic treatment
Phase 2
- Conditions
- Health Condition 1: K518- Other ulcerative colitis
- Registration Number
- CTRI/2024/05/067117
- Lead Sponsor
- Dept of Shalya Tantra
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Age 18 years of age - 60 years of age
2. Irrespective of caste, religion , sex mild to moderate cases of ulcerative colitis (mayo’s score 3-10 and true and witts criteria)
3.previous diagnosed case of ulcerative colitis.
Exclusion Criteria
1.patient above 60 years and below 18 years of age
2.Toxic mega colon/ Fulminant type of disease
3.Severe type of Ulcerative colitis (Mayo score 11-12)
4.Known active infection (TB, HIV, C. Dificile, CMV)
5.Gastro intestinal perforation
6.Infective colitis, ischemic colitis, solitary ulcer syndrome, irradiation colitis
7.Lactose intolerance.
8.Pregnant females
9.known malignancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Disease specific subjective parameters on true love’s and witts score . <br/ ><br>Colonoscopic tissue biopsy for diagnosis of ulcerative colitis <br/ ><br>Colonoscopic Mayo’s scoring for disease activityTimepoint: oral medications for period of 12 weeks followed by follow up every 4 weeks once for period of 12 weeks
- Secondary Outcome Measures
Name Time Method Assessment of disease activity by follow up colonoscopy by mayos scoring assessment <br/ ><br>Assessment of symptoms of disease via subjective parameters using true loves & witts criteriaTimepoint: After 12 weeks drug will be further continued for 24 weeks with 4 weeks follow up to avoid relapse