Optimal timing of solid food introduction to infants at high risk of developing allergic disease.

Not Applicable

• Conditions: Eczema; Inflammatory and Immune System - Allergies; Skin - Dermatological conditions; Egg allergy

• Registration Number: ACTRN12609000415202
• Lead Sponsor: Women's and Children's Health Research Insitute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-06-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 226

Inclusion Criteria

Term singleton infants
Infants with symptoms of moderate to severe eczema
Both breastfed and formula fed infants

Exclusion Criteria

Infants who have commenced any solids prior to 4 months of age
Infants who have commenced egg containing solids prior to study entry
Infants who have any congenital or acquired disease or developmental disorder likely to affect infant feeding

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Immunoglobulin E (IgE) mediated egg allergy defined as an allergic reaction to a raw egg challenge and associated evidence of sensitisation to egg assessed by skin prick testing where a positive skin prick test has a mean weal diameter >3mm to egg. An allergic reaction will be defined as at least 3 concurrent non-contact urticaria persisting for at least 5 minutes and/or generalised skin erthema and/or vomiting and/or anaphylaxis (evidence of circulatory or respiratory involvement) within 2 hours of ingestion of raw egg[At 12 months of age]