A multicenter randomized controlled trial comparing intermittent enteral feeding while in right lateral tilt position to standard care among mechanically ventilated adult ICU patients

John Hunter Hospital0 个研究点目标入组 120 人开始时间: 2016年2月17日最近更新: 2020年1月13日

试验速览

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•1) Patients who are receiving invasive mechanical ventilation (IMV) and are deemed likely to require IMV for at least the next 24 hours.
•2) Age equal to or more than 18 years
•3) Naso or Oro-gastric tube is in situ or its insertion is imminent

•1) Patients with ICU stay of more than 72 hours after initiation of IMV
•2) Moribund patients or those patients with an imminent risk of death within the next 48 hours.
•3) Patients who are not deemed fit for enteral feeding by the treating team.
•4) Patients with history of esophageal or gastric surgery within the last month.
•5) Patients with gastric banding procedure
•6) Patients with acute starvation (i.e., no nutrition for >5 days)
•7) Patients who had intestinal resection with less than 200 cm of small intestine remaining.
•8) Patients with known hiatus hernia.
•9) Patients with feeding jejunostomy tubes in situ.
•10) Patients receiving total parenteral nutrition.
•11) Patients who suffer from cachexia or severely malnourished state
•12) Patients with history of malabsorptive or gastrointestinal motility disorders (e.g. irritable bowel syndrome or inflammatory bowel diseases or diabetic gastroparesis)
•13) Patients in whom semi-recumbent right lateral position is contraindicated or not feasible.
•14) Treating clinician lacks equipoise or believes that bolus/ intermittent feeding is not in patient’s best interests

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