MedPath

Procyanidin B2 Enriched Cocoa Effects on Mitochondrial Biogenesis

Not Applicable
Completed
Conditions
Athletes
Registration Number
NCT04301583
Lead Sponsor
Universidad Europea de Madrid
Brief Summary

The purpose of this study is to test how cocoa-rich procyanidin B2 affect the mitochondrial exercise adaptations.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
38
Inclusion Criteria
  • Men/Women
  • Age between 18 and 45 years
  • Aerobic power of oxygen consumption greater than or equal to 55 mL / kg / min
Exclusion Criteria
  • Smoke
  • Any chronic disease
  • Intake of nutritional or ergogenic supplements
  • Chronic medication
  • Cocoa allergy

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Difference in mitochondrial number10 weeks

Number of mitochondria in blood cells measured by qPCR using mitochondrial COX1 gene and beta globin as housekeeping nuclear gene

Difference in exercise performance10 weeks

Maximum oxygen consumption

* of incomplete pulmonary gas exchange on VO2 max - Powers - Citado por 318

* determination of cardiorespiratory fitness and training ... - Clark - Citado por 180 Maximum oxygen consumption

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Universidad Europea de Madrid

🇪🇸

Villaviciosa de Odón, Madrid, Spain

Universidad Europea de Madrid
🇪🇸Villaviciosa de Odón, Madrid, Spain

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.