Psychotherapy in non-affective psychotic outpatients

Not Applicable

• Conditions: F20; F25; Schizophrenia; Schizoaffective disorders

• Registration Number: DRKS00015627
• Lead Sponsor: Evangelisches Klinikum Bethel (EvKB), Klinik für Psychiatrie und Psychotherapie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-10-04
• Study Completion: 2023-07-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 130

Inclusion Criteria

diagnosis of schizophrenia (ICD-10: F20) or schizoaffective disorder (ICD-10: F25); age between 18 and 65 years, willingness to undergo random allocation to 20 sessions of outpatient psychotherapy (CBT) or psychiatric outpatient TAU; written informed consent; sufficient knowledge of written and spoken German

Exclusion Criteria

current diagnosis of substance dependence; organic brain disease, serious and acute somatic illness, serious eating disorder (BMI < 15); acute suicidality at baseline, outpatient psychotherapy within the last two years

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The Positive and Negative Syndrome Scale assessed by the Structured Clinical Interview for the Positive and Negative Syndrome Scale (SCI-PANSS, Kay, Opler, & Fiszbein, 1992) is the primary outcome measure to quantify changes in schizophrenia symptoms at post-treatment (6 month after baseline) and at follow-up (12 month after baseline).

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes include the cost-effectiveness of the CBT-treatment and the number of re-hospitalisations (efficiency of CBT).