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Clinical Trials/NCT04816409
NCT04816409
Completed
N/A

Effect of Neuro Developmental Therapy to Improve Postural Reactions and Motor Milestones in Infants With Down Syndrome

Riphah International University1 site in 1 country20 target enrollmentMarch 15, 2019
ConditionsDown Syndrome

Overview

Phase
N/A
Intervention
Not specified
Conditions
Down Syndrome
Sponsor
Riphah International University
Enrollment
20
Locations
1
Primary Endpoint
Gross Motor Function Measure-88(GMFM-88)
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

Neurodevelopmental treatments are a progressive therapeutic method experienced thru qualified therapists for the improvement in affected ones. The most important trial in Down syndrome children is motor milestones and postural reactions to develop on time.

Neurodevelopmental therapy is applied to accurate atypical postural tone and to enable further regular motion for execution of presentation of abilities. Objective: To determine the effects of Neuro Developmental therapy in improving postural reaction and motor milestones in infants with Down syndrome.

Detailed Description

This study was a randomized trial design. This study was conducted in Rehab Care Physiotherapy Department. 20 Children with Down syndrome meeting the predetermined inclusive and exclusive criteria were arbitrarily allocated into dual batches through convenient sampling technique. The first batch which was the experimental group was given Neurodevelopmental therapy and the duration of the treatment comprised of 1.5 hour, three days a week for 6 weeks. The second group which was the control group received conventional therapy and the period of the ministrations comprised of 1 hour, with 10 repetition 3 sets for each muscle three days a week for 1.5 months, Pre-assessment and post-assessment was evaluated through Gross motor function-88. Recorded values were analyzed through SPSS.

Registry
clinicaltrials.gov
Start Date
March 15, 2019
End Date
January 30, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Trisomy 21 by genetic karyotype.
  • Down syndrome children with delayed milestone.
  • Definite identification of Down syndrome by neurologist.
  • Children having the average birth weight above 2.500 grams and average birth length above 49.52 cm.
  • Laxity, low muscle tone and psychomotor development deficits

Exclusion Criteria

  • Infants with Heart Defect.
  • Critical orthopedic difficulties or deformities (hip instability, patellar instability, foot deformity).
  • Unrestrained thyroid conflicts.
  • Perilabour asphyxia (Apgar of minutes 1 and 5 equal to or less than 7).
  • Critical optical or acoustic disorders.
  • Mass below the 3rd percentage of Down syndrome

Outcomes

Primary Outcomes

Gross Motor Function Measure-88(GMFM-88)

Time Frame: 2 months

The GMFM-88 is the original 88-item measure. Items span the spectrum of gross motor activities in five dimensions. ... The GMFM-66 is a 66 item subset of the original 88 items identified through Rasch analysis to best describe the gross motor function of children with cerebral palsy of varying abilities.

Study Sites (1)

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