EUCTR2010-023508-28-GB进行中（未招募）1 期
A CLINICAL TRIAL OF THE INTRA-TUMOURAL CONCENTRATION AND ACTIVITY OF NILOTINIB IN INTRA-CUTANEOUS SCHWANNOMAS - PHNT NilotinibNF2
Plymouth Hospital NHS Trust0 个研究点目标入组 5 人开始时间: 2010年11月30日最近更新:
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 5
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
入选标准
- •oMale and female patients who fulfil diagnostic criteria for NF2
- •oMinimum age 18 years
- •oPresence of at least one CS accessible for biopsy
- •oKarnofski performance status above 60%.
- •oAdequate organ function.
- •oAble to swallow tablets
- •oAcceptable birth control methods
- •oNegative pregnancy test
- •Are the trial subjects under 18? no
- •Number of subjects for this age range: 0
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 0
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range 0
排除标准
- •oHypersensitivity to nilotinib or any of its excipients
- •oPregnant or lactating females
- •oPatients taking concomitant warfarin
- •oSerious uncontrolled concomitant medical or psychiatric illness.
- •oImpaired cardiac function
研究者
相似试验
进行中（未招募）
1 期
Investigation of the intra-tumoural concentration and activity of sorafenib in cutaneous schwannomas - Sorafenib in NF2eurofibromatosis, type 2 (acoustic neurofibromatosis)MedDRA version: 14.0 Level: LLT Classification code 10029271 Term: Neurofibromatosis, type 2 (acoustic neurofibromatosis) System Organ Class: 10010331 - Congenital, familial and genetic disordersEUCTR2011-001789-16-GBPlymouth Hospital NHS Trust14
已完成
4 期
Activity of sorafenib in schwannomasCancerISRCTN49989464Plymouth Hospitals NHS Trust (UK)14
进行中（未招募）
不适用
A phase II Clinical Trial to Evaluate Intratumoral Injection of a Depot Formulation of Paclitaxel (DTS-301) as Neoadjuvant Therapy of Patients with Breast CancerInvasive primary breast cancerEUCTR2005-001417-18-HUDIATOS S.A.10
进行中（未招募）
不适用
A Phase II Clinical Trial to Evaluate Intratumoral Injection of a Depot Formulation of Paclitaxel (DTS-301) as Neoadjuvant Therapy of Patients with Breast CancerInvasive primary breast cancerEUCTR2005-001417-18-ATDIATOS S.A.10
进行中（未招募）
1 期
Phase 1b/2 Study of V937 Injected into Tumors in Combination with Intravenous (IV) PembrolizumabAdvanced/metastatic solid tumorsMedDRA version: 21.1Level: LLTClassification code 10065252Term: Solid tumorSystem Organ Class: 100000004864EUCTR2020-001908-42-PLMerck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc185