Effect of Action Observation and Motor Imagery Therapy on Balance, Functional Status and Quality of Life in Parkinson's Disease, Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Parkinson's Disease
- Sponsor
- Karamanoğlu Mehmetbey University
- Enrollment
- 54
- Locations
- 1
- Primary Endpoint
- The difference in the scores of the Timed Up and Go Test between pre- and post-rehabilitation assessments
- Status
- Recruiting
- Last Updated
- 4 months ago
Overview
Brief Summary
In recent years, motor imagery (MI) and action observation (AO) therapy strategies have been used in rehabilitation programs to increase motor learning in Parkinson's disease (PD). Visuomotor training strategies such as AO and MI therapy rely on the activity of the mirror neuron system to facilitate motor re-learning. Mirror neurons are activated during the performance of goal-directed actions, also when observing the same action and visualizing the action in the mind.
The aim of this clinical trial is to test whether the application of AO and MI treatment in PD in addition to conventional rehabilitation programs has an additional effect on Balance, Functional Status and Quality of Life.
Detailed Description
Parkinson's disease (PD) is a neurodegenerative disease with a chronic and progressive course. Freezing phenomena, gait disorders, and balance problems are common in PD. Gait and balance disorders and motor freezing attacks that occur as a result of PD increase the risk of falling, leading to a decrease in functional independence and quality of life. The main goal of Parkinson's rehabilitation is to ensure the maximum functional status and independence in daily living activities and to increase their quality of life. In recent years, motor imagery (MI) and action observation (AO) therapy strategies have been used in rehabilitation programs to increase motor learning in PD. Visuomotor training strategies such as AO and MI therapy rely on the activity of the mirror neuron system to facilitate motor re-learning. Mirror neurons are activated during the performance of goal-directed actions, also when observing the same action and visualizing the action in the mind. The aim of this clinical trial is to test whether the application of AO and MI treatment in PD in addition to conventional rehabilitation programs has an additional effect on Balance, Functional Status and Quality of Life.
Investigators
Yurdagül Bahran Muştu
M.D., Principal investigator
Karamanoğlu Mehmetbey University
Eligibility Criteria
Inclusion Criteria
- •Patients with a diagnosis of Parkinson's Disease
- •Hoehn and Yahr Stage 1-3
Exclusion Criteria
- •Patients with cognitive dysfunction (those who cannot follow simple verbal instructions)
- •Patients with severe hearing problems
- •Patients with severe vision problems
- •Patients with additional musculoskeletal system pathology that will affect physical performance (such as amputation, severe joint mobility limitation, peripheral nerve damage)
- •Patients with uncontrolled hypertension and diabetes mellitus
- •Patients with a history of symptomatic lung disease (such as asthma, chronic obstructive pulmonary disease, emphysema)
- •Patients with a history of symptomatic cardiac disease (such as coronary artery disease, arrhythmia, heart failure)
Outcomes
Primary Outcomes
The difference in the scores of the Timed Up and Go Test between pre- and post-rehabilitation assessments
Time Frame: 6 weeks
Univariate statistical analyses will be performed to calculate differences in the scores of the Timed Up and Go Test between pre- and post-rehabilitation assessments
The difference in the scores of the Berg Balance Scale between pre- and post-rehabilitation assessments
Time Frame: 6 weeks
Univariate statistical analyses will be performed to calculate differences in the scores of the Berg Balance Scale between pre- and post-rehabilitation assessments. Berg Balance Scale consists of 14 items. Total score ranges from 0 to 56. Higher scores indicate better balance.
The difference in the scores of the Five Times Sit to Stand Test between pre- and post-rehabilitation assessments
Time Frame: 6 weeks
Univariate statistical analyses will be performed to calculate differences in the scores of the Five Times Sit to Stand Test between pre- and post-rehabilitation assessments
The difference in the scores of the The Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale pre- and post-rehabilitation assessments
Time Frame: 6 weeks
Univariate statistical analyses will be performed to calculate differences in the scores of the The Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale between pre- and post-rehabilitation assessments. The Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) consists of four sections: Part 1: non-motor experiences of daily living, Part 2: motor experiences of daily living, Part 3: motor examination, Part 4: motor complications. It consists of a total of 50 questions. In this study, sections II (motor experiences of daily living) and III (motor examination) will be used. Each item is is scored between 0 and 4. Higher values indicate that the patient's condition is worse.
Secondary Outcomes
- The difference in the scores of the Parkinson's Disease Questionnaire between pre- and post-rehabilitation assessments(6 weeks)
- The difference in the scores of the Freezing of Gait Questionnaire between pre- and post-rehabilitation assessments(6 weeks)