Can targeted cognitive training alleviate symptoms of freezing of gait in patients with Parkinson's Disease?
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 65
研究概览
简要总结
This study aimed to trial a program of brain training to improve the symptom of freezing of gait in Parkinson's disease. Freezing of gait is a common symptom of Parkinson's disease, which leaves a patient unable to walk forward, and becoming 'stuck' on the spot. This can lead to falls and loss of independence. Unfortunately, the symptom is not well treated. Recent research suggests freezing is linked to problems with attention. Our trial therefore aimed to improve attention and other relevant processes in the brain by using computer exercises to try and reduce the severity of freezing of gait. We recruited participants who completed a 7 week program, including training twice a week. One group completed specific exercises aimed at improving attention and freezing, while another 'control group' completed more general exercises on a computer. The results showed that individuals in the group completing specific computer exercises had a reduced severity of freezing at the end of the trial, as measured by different walking exercises. The results are preliminary due to a small sample size, but are suggestive of a potentially beneficial treatment for freezing.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit(—)
- 性别
- All
入选标准
- •This study will recruit 100 PD patients with a clinical history of FOG. We aim to recruit participants based on information obtained from medical assessments (including subjective report of symptoms and Mini Mental State Examination (MMSE) score of 24 or greater) as well as self-report measures of freezing (e.g. a positive score on question 3 of the FOG Questionnaire) completed at the PD Research Clinic located at the Brain and Mind Centre.
排除标准
- •MMSE of less than 24
