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临床试验/ACTRN12613000359730
ACTRN12613000359730
已完成
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Can targeted cognitive training alleviate symptoms of freezing of gait in patients with Parkinson's Disease?

Professor Simon JG Lewis0 个研究点目标入组 65 人2013年4月5日

概览

阶段
未知
干预措施
未指定
疾病 / 适应症
Freezing of Gait in Parkinson's Disease
发起方
Professor Simon JG Lewis
入组人数
65
状态
已完成
最后更新
6年前

概览

简要总结

This study aimed to trial a program of brain training to improve the symptom of freezing of gait in Parkinson's disease. Freezing of gait is a common symptom of Parkinson's disease, which leaves a patient unable to walk forward, and becoming 'stuck' on the spot. This can lead to falls and loss of independence. Unfortunately, the symptom is not well treated. Recent research suggests freezing is linked to problems with attention. Our trial therefore aimed to improve attention and other relevant processes in the brain by using computer exercises to try and reduce the severity of freezing of gait. We recruited participants who completed a 7 week program, including training twice a week. One group completed specific exercises aimed at improving attention and freezing, while another 'control group' completed more general exercises on a computer. The results showed that individuals in the group completing specific computer exercises had a reduced severity of freezing at the end of the trial, as measured by different walking exercises. The results are preliminary due to a small sample size, but are suggestive of a potentially beneficial treatment for freezing.

注册库
who.int
开始日期
2013年4月5日
结束日期
2015年10月7日
最后更新
6年前
研究类型
Interventional
性别
All

研究者

发起方
Professor Simon JG Lewis

入排标准

入选标准

  • This study will recruit 100 PD patients with a clinical history of FOG. We aim to recruit participants based on information obtained from medical assessments (including subjective report of symptoms and Mini Mental State Examination (MMSE) score of 24 or greater) as well as self\-report measures of freezing (e.g. a positive score on question 3 of the FOG Questionnaire) completed at the PD Research Clinic located at the Brain and Mind Centre.

排除标准

  • MMSE of less than 24

结局指标

主要结局

未指定

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