Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon
- Conditions
- Hand LacerationTendon InvolvedClean LacerationNo Bone Involved
- Interventions
- Drug: Antibiotic-Cefamezin
- Registration Number
- NCT01899781
- Lead Sponsor
- HaEmek Medical Center, Israel
- Brief Summary
The investigators assume that simple hand lacerations involving flexors or extensors tendons, do not require prophylactic antibiotic treatment to prevent wound infection.
- Detailed Description
Hand lacerations are divided to "complicated" which involves tendons, nerves, bones, and joints, and "simple" which involves only cutaneous and subcutaneous tissue.
prophylactic antibiotic should not be given in a clean simple lacerations, and should be given when a bone is involve (open fracture). But there is not enough data, weather prophylactic antibiotic treatment should be given when only tendons are involved. The investigators will examine 2 groups of 30 patients each with clean hand lacerations involving tendons. One group will be treated with prophylactic antibiotic and the other wont be treated, randomly. The investigators assume that the rate of wound infection wont be different between the 2 groups.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 24
- Hand laceration
- Tendon involeved
- Clean laceration
- No bone involved
- Pregnant
- Children
- Immunocompremised patients
- "Dirty" lacerations
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description with antibiotic and without antibiotic Antibiotic-Cefamezin -
- Primary Outcome Measures
Name Time Method rate of wound infections 2 years signs of wound/tissue infection, levels of WBC, ESR, CRP
- Secondary Outcome Measures
Name Time Method