NIRS Monitoring During Intracranial Interventions

• Conditions: Intracranial Arteriovenous Malformation; Subarachnoid Hemorrhage

• Registration Number: NCT03367975
• Lead Sponsor: University Hospital, Bonn

Brief Summary

Near infrared spectroscopy is a valuable tool to monitor cerebral oxygenation during intracranial interventions. However, it yields artificial results when the dye indocyanine green (ICG) is applied, which is routinely done for intraoperative angiography.

The investigators examine, to what extent and which duration NIRS is disturbed following ICG application.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-03
• Study First Submitted: 2014-10-03
• Status Verified: 2017-12
• Study First Submitted QC: 2017-12-04
• Last Update Submitted: 2017-12-04
• Study First Posted: 2017-12-11
• Last Update Posted: 2017-12-11
• Primary Completion: 2018-01
• Study Completion: 2018-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• patients scheduled for aneurysm clipping or av-malformation removal

Exclusion Criteria

• pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
amount of rSO2 - change [%] induced by ICG-application	1 hour	Cerebral oxygenation (rSO2) may be quantified using NIRS. The dye ICG, that is used intraoperatively, affects NIRS, since it changes rSO2 without modifying cerebral oxygenation. The amount, by which rSO2 is altered will be assessed

Trial Locations

Locations (1)

Dept. of Anaesthesiology and Intensive Care Medicine, Univ. of Bonn; 🇩🇪 Bonn, Germany