Pleural Disease: Phenotypes, Diagnostic Yield and Outcomes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Resolution of pleural disease
研究概览
简要总结
Pleural disease i.e. with effusions or pneumothorax have a high disease burden to patients. This is because most patients require diagnostic and therapeutic interventions in the form of drainage and biopsies. With increasing age, the incidence of pleural disease is likely to rise with concomitant rise in pulmonary malignancy and infection.
The impact of pleural disease, especially ambulatory drainage depends not only on patient factors such as effusion size, cardiopulmonary co-morbidities and underlying aetiology. It also depends on socioeconomic factors such as ability to afford ambulatory equipment (which is not covered by Medisave), availability of care-givers and coping mechanisms.
To phenotype patients presenting to Singapore General Hospital with pleural disease and evaluate impact on outcomes of pleural interventions
This study will collect existing or prospective data that is part of standard clinical care
- Source of the data: electronic medical record of patients (ambulatory and inpatient)
- Data will be collected prospectively.
详细描述
- BACKGROUND AND RATIONALE
Pleural disease i.e. with effusions or pneumothorax have a high disease burden to patients. This is because most patients require diagnostic and therapeutic interventions in the form of drainage and biopsies. With increasing age, the incidence of pleural disease is likely to rise with concomitant rise in pulmonary malignancy and infection.
The impact of pleural disease, especially ambulatory drainage depends not only on patient factors such as effusion size, cardiopulmonary co-morbidities and underlying aetiology. It also depends on socioeconomic factors such as ability to afford ambulatory equipment (which is not covered by Medisave), availability of care-givers and coping mechanisms.
Therefore, translating internationally accepted pleural interventions into an Asian context, moreover a Singaporean one, is challenging. 2. HYPOTHESIS AND OBJECTIVES
Asian patients with pleural disease have unique phenotypes and outcomes from pleural interventions
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 16 Years 至 100 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The subject must meet all of the following inclusion criteria to participate in this study.
- •Evidence of pleural disease on chest radiograph or bedside ultrasound or Computed Tomography regardless of underlying aetiology
- •No age or gender restrictions
- •Ability to provide informed consent
排除标准
- •Subjects who no radiographic evidence of pleural disease or who are unwilling/unable to provide informed consent
结局指标
主要结局
Resolution of pleural disease
时间窗: 30 days
As above
次要结局
未报告次要终点