Taiwan Real-world LDCT Screening Behavior and Outcome Research for High Risk Subjects Based on Health Promotion Administration
- Conditions
- Lung CancerHigh-Risk CancerSmokingPollutionExposureFamily Relations
- Registration Number
- NCT05557487
- Lead Sponsor
- Gee-Chen Chang
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 6618
Inclusion Criteria:<br><br>Group 1: Previous heavy smokers Age 50 to 80 years, meet both criteria in the followings.<br><br> 1. Cigarette smoking of at least 20 pack-years<br><br> 2. With successful smoking cessation history (stopping smoking for more than 6 months),<br> but less than 15 years<br><br>Group 2: First-degree relatives of lung cancer patients<br><br> 1. aged more than 50 years<br><br> 2. age less than 50 years old, but older than the age at diagnosis of the youngest lung<br> cancer proband in the family<br><br>Group 3: With other high-risk occupational or environmental factors Age 50 to 80 years,<br>meet one or more of the following criteria.<br><br> 1. air-pollution exposed occupations (such as traffic policemen, and street<br> cleaners....) for at least 10 years<br><br> 2. cooking index = 110, defined as 2/7 * days cooking by pan frying, stir-frying, or<br> deep frying in one week * years cooking.<br><br> 3. cooking without using ventilation for more than 20 years<br><br> 4. history of pulmonary tuberculosis and complete anti-tuberculosis treatment with<br> intervals more than 5 years before this study<br><br>Exclusion Criteria:<br><br> 1. previous history of lung cancer<br><br> 2. another malignancy except for cervical carcinoma in situ or non-melanomatous<br> carcinoma of the skin within 5 years<br><br> 3. an inability to tolerate transthoracic procedures or thoracotomy<br><br> 4. chest CT examination was performed within 18 months<br><br> 5. hemoptysis of unknown etiology within one month<br><br> 6. body weight loss of more than 6 kg within one year without an evident cause<br><br> 7. a known pregnancy<br><br> 8. Not capable of understanding or responding to the written questionnaire even through<br> the help from the study team
Not provided
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The rate of willingness and completeness of LDCT screening after the detailed questionnaire survey for the eligible participants.;To investigate overall lung cancer detection rate of high lung cancer risk individuals
- Secondary Outcome Measures
Name Time Method