Late Mortality, Burden of Morbidity and Quality of Life in Long Term Survivors of Hematopoietic Cell Transplantation: Experience from A Single Centre in India

Hematologic stem cell transplantation (HCT) remains the only curative option for many malignant and non-malignant hematologic disorders. However, relapse, infection, graft versus host disease, endocrinopathies  and second malignancies are important cause of mortality and long term morbidity in these patients. Survivors of HCT also face significant social and economic hardships post-transplant. There is limited information on outcomes of long term survivors of HCT from India. With the rising number of transplants being done across the country, it is important to study the incidence and cause of late mortality, burden of morbidity, functional rehabilitation and quality of life after HCT in our patients. In this observational study, long term survivors who underwent HCT at ACTREC will be interviewed about their physical and social well-being. The study participants will not be subjected to any additional follow up visits, investigations or treatment as part of this study. Information obtained from this study might help the healthcare providers and policy makers understand the burden of morbidity and mortality post-transplant and in the allocation of resources towards the long-term care of HCT survivors

In this study, we look at the long term outcomes of patients who underwent autologous or allogeneic transplant at our center and survived for more than 2 years post-transplant.