Evaluation of Skeletal Muscle Function Using Ultrasonic Elastography
Not yet recruiting
- Conditions
- Chronic Obstructive Pulmonary Disease
- Interventions
- Other: pulmonary rehabilitation
- Registration Number
- NCT05805332
- Lead Sponsor
- China-Japan Friendship Hospital
- Brief Summary
The goal of observational study is to evaluation of skeletal muscle function in patients with chronic obstructive pulmonary disease before and after lung rehabilitation training using ultrasonic elastography in Chronic Obstructive Pulmonary Disease. The main question it aims to answer are:Evaluation of skeletal muscle function in patients with chronic obstructive pulmonary disease before and after lung rehabilitation training using ultrasonic elastography.
Participants will undergo pulmonary rehabilitation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- The age is between 40-80 years old
- Patients with chronic obstructive pulmonary disease who meet the diagnostic criteria of GOLD guideline(2019)
- There was no acute exacerbation in the past 12 weeks
Exclusion Criteria
- Hypoxemia (oxygen partial pressure is less than 60mmHg or oxygen saturation is less than 88% at rest), or patients who need continuous oxygen inhalation, or patients with any contraindication to exercise test (refer to the American Thoracic Association/American Association of Thoracic Physicians exercise test guidelines)
- Oral glucocorticoids
- Receive long-term oxygen therapy prescription
- Have participated in supervised exercise programs in the past 12 months
- History of other lung diseases, including pneumoconiosis, bronchiectasis, tuberculosis, primary pulmonary hypertension, pulmonary embolism, interstitial lung disease
- Diseases that restrict the active exercise ability of participants or involve skeletal, neuromuscular, cardiovascular or metabolic disorders of muscle activity, such as tumors, diabetes, muscle weakness, etc
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description pulmonary rehabilitation pulmonary rehabilitation -
- Primary Outcome Measures
Name Time Method Effectiveness of pulmonary rehabilitation training 1 week after pulmonary rehabilitation 6-30-second sit-to-stand test
- Secondary Outcome Measures
Name Time Method Forced Expiratory Volume in 1-second(FEV1) 1 week after pulmonary rehabilitation Pulmonary function test
Ultrasonic elastic imaging of rectus femoris 1 week after pulmonary rehabilitation Ultrasonic elastography of skeletal muscle