Effects of Descending Stair Walking on Cardiometabolic Adaptations Among Obese, Untrained Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- High-Density Lipoprotein Cholesterol
研究概览
简要总结
The global rise in the prevalence of physical inactivity is major public health concern. Lifestyle-related activities, such as stairs walking, has important public health implications and may represent an alternative approach for those who have difficulty adhering to conventional exercise programs. This two-armed, parallel-group, randomized controlled trial (RCT) aims to assess and compare the effects between the descending stair walking (DSW) and ascending stair walking (ASW) on cardiometabolic health markers, cardiopulmonary capacity, body composition and muscular strength.
This RCT will recruit 16 obese inactive and sedentary females will be randomized using permuted block randomization into two arms: intervention arm, DSW and active comparator arm: ASW in a 1:1 allocation ratio. The participants in the DSW and ASW arms will undergo twice a week stair walking intervention session for 8 weeks. The exercise volume will be gradually increased over 8 weeks by increasing the number of repetitions by two every week for both arms. Borg's scale of perceived exertion (RPE) and visual analogue scale (VAS) will be used to assess subjective intensity of stair walking and pain intensity immediately after each repetition. Assessments will be carried out through two time points, pre-intervention assessment (T0) and immediately after completion of the intervention at 8 weeks (T1). During each assessment, the primary outcome to be assessed includes the cardiometabolic health markers and cardiopulmonary capacity, while the secondary outcomes to be assessed are the body composition and muscular strength. Whereas during the intervention, continuous heart rate and gas consumption will be monitored at week 1 (W1), week 4 (W4) and week 8 (W8) to monitor the intensity of the exercise.
详细描述
1.2 Research Objectives
1.2.1 General Objective (i) The study compares the impact of the 8-week descending stair walking (DSW) and ascending stair walking (ASW) on cardiometabolic health in obese, untrained women.
1.2.2 Specific Objective
To compare the effect of DSW & ASW on:
(i) cardiometabolic health (fasting plasma glucose, lipid profile, renal profile, cardiorespiratory fitness, resting blood pressure, resting energy expenditure, resting heart rate) (ii) body composition (fat mass, lean body mass, waist circumference, hip circumference, thigh circumference) (iii) muscular fitness & functional capacity (back and leg strength & 6-min walking test)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •age 18-50-year-old
- •BMI 25.0 - 39.9 kg/m2,
- •body fat percentage > 30%
- •no lower limb orthopaedic injuries
- •sedentary lifestyle (regular exercise <1 h per week).
排除标准
- •taking supplements or medication known to affect REE (such as oral contraceptives),
- •severe medical conditions affecting their physical or mental health
- •individuals with implanted medical device
- •suffer from alcohol or drug abuse and
- •trying to conceive/ pregnant or breastfeeding
研究组 & 干预措施
DSW
Descending Stair Walking
干预措施: DSW (Other)
ASW
Ascending Stair Walking
干预措施: ASW (Other)
结局指标
主要结局
High-Density Lipoprotein Cholesterol
时间窗: 8 weeks
Changes in High-Density Lipoprotein Cholesterol (mmol/L) from baseline
Fasting Plasma Glucose
时间窗: 8 weeks
Changes in Fasting Plasma Glucose (mmol/L) from baseline
Total Cholesterol
时间窗: 8 weeks
Changes in Total Cholesterol (mmol/L) from baseline
Low-Density Lipoprotein Cholesterol
时间窗: 8 weeks
Changes in Low-Density Lipoprotein Cholesterol (mmol/L) from baseline
Alanine Aminotransferase
时间窗: 8 weeks
Changes in Alanine Aminotransferase (U/L) from baseline
Alanine Aspartate transaminase
时间窗: 8 weeks
Changes in Alanine Aspartate transaminase (U/L) from baseline
Trigliceride
时间窗: 8 weeks
Changes in Trigliceride (mmol/L) from baseline
Resting Blood Pressure
时间窗: 8 weeks
Changes in Resting Diastolic and Systolic Blood Pressure (mm/Hg) from baseline
Resting Heart Rate
时间窗: 8 weeks
Changes in Resting Heart Rate (beat.min) from baseline
Resting Energy Expenditure
时间窗: 8 weeks
Changes in Resting Energy Expenditure (kcal/day) from baseline
Resting energy oxidation
时间窗: 8 weeks
Changes in fat and charbohydrate oxidation from baseline
次要结局
- Lean Body Mass(8 weeks)
- Isometric Muscular Strength(8 weeks)
- Cardiorespiratory Capacity-6 Minute Walking Test(8 weeks)
- Body Mass Index (BMI)(8 weeks)
- Percentage body fat(8 weeks)
- Hip Circumference(8 weeks)
- Body Mass(8 weeks)
- Waist Circumference(8 weeks)
- Training substrate oxidation(8 weeks)
研究者
Nazirah Gulam Mohamed
Principal Investigator
Universiti Sains Malaysia
