Characterization of White Blood Cells Sub-populations From Multiple Sclerosis Patients.
- Conditions
- Multiple Sclerosis
- Interventions
- Other: Blood SamplingOther: CSF Sampling
- Registration Number
- NCT03486665
- Lead Sponsor
- Bioimmunate
- Brief Summary
Multiple sclerosis (MS) is a chronic progressive neurological autoimmune disease, that gradually affects patient's quality of life. There are about 2.5 millions patients world wide, with an increasing cost Burdon. Up to date, it remains unclear who are the exact cells to initiate the disease. During the disease, the repertoire of cells expands and undergoes changes. The purpose of this study is to characterize those changes.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Patients with diagnosis of MS according to the revised criteria of McDonald or healthy volunteers
- Ability to provide written informed consent.
Exclusion Criteria
- Active malignant disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Diagnosed with Multiple Sclerosis Blood Sampling Patients previously diagnosed with Multiple Sclerosis Healthy Volunteers Blood Sampling Health volunteers who do not have an autoimmune diseases, including Multiple Sclerosis Newly Diagnosed with Multiple Sclerosis Blood Sampling Patients diagnosed for the first time with Multiple Sclerosis and hospitalized Newly Diagnosed with Multiple Sclerosis CSF Sampling Patients diagnosed for the first time with Multiple Sclerosis and hospitalized
- Primary Outcome Measures
Name Time Method Quantification of disease related white blood cells from blood and/ or CSF through study completion, an average of 6 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hadassah Medical Center
🇮🇱Jerusalem, Israel