Multi center clinical study of Shenfu Xiangshao Decoction in the treatment of coronary heart disease complicated with heart failure
- Conditions
- heart failure
- Registration Number
- ITMCTR2000003670
- Lead Sponsor
- Shanghai Putuo District Central Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Male
- Target Recruitment
- Not specified
1) They are over 18 years old and have no gender limit;
2) Left ventricular ejection fraction (LVEF) was less than 50% (echo);
3) Patients with chronic heart failure and NYHA class II or above have symptoms of chest tightness / shortness of breath / fatigue / hyperhidrosis;
4) Definite diagnosis of coronary heart disease (including history, clinical symptoms, signs, imaging examination);
5) Understand and sign the informed consent form.
1) NYHA class I patients had no clinical symptoms;
2) Patients who planned to undergo revascularization in recent 2 months;
3) Patients preparing for heart transplantation or CRT;
4) Patients with acute pulmonary edema or acute hemodynamic disorder;
5) Patients with strict liquid intake limit not exceeding 500ml / day;
6) Women who have or plan to become pregnant;
7) Those who have participated in any drug clinical trials within the first 3 months;
8) The survival time was less than 2 months;
9) According to the investigator's judgment, the patient could not complete the study or could not comply with the requirements of this study.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 6-minute walking distance;Ejection fraction;
- Secondary Outcome Measures
Name Time Method Quality of life score;NT-proBNP;All cause mortality;TCM syndrome score;Readmission for worsening heart failure;