The evaluation of esomeprazole efficacy in treatment of early onset pre-eclampsia
Phase 3
Recruiting
- Conditions
- Preeclampsia.Eclampsia in pregnancy
- Registration Number
- IRCT2017082333680N2
- Lead Sponsor
- Vice chancellor for research, Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 46
Inclusion Criteria
Preeclampsia diagnosis; hypertensive pregnancy; gestational age between 26 to 32 weeks; single-crowned pregnancy; no need to terminate the pregnancy in the next 48 hours; absence of anomalies in the fetus; patient satisfaction for expected treatment;
Exclusion criteria: Eclampsia; uncontrolled blood pressure; pulmonary edema; cerebrovascular accidents; heart failure; HELLP syndrome; use of proton pump inhibitors; renal failure; uncertain tests for the evaluation of embryo's health
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of admission to delivery. Timepoint: before intervention until delivery. Method of measurement: Pregnancy termination.
- Secondary Outcome Measures
Name Time Method Frequency of maternal and fetal complications in patients with preeclampsia. Timepoint: before intervention until delivery. Method of measurement: Questionnaire and checklist.;Biomarker level of tyrosine kinase and endoglycine. Timepoint: after Intervention. Method of measurement: Blood test.