Clinical outcomes and safety of preoperative non-preserved steroid eye drop in trabeculectomy: A randomised controlled trial
- Conditions
- Due to COVIDᆧ pandemic,the collection and other process may be delayed. Some patients visits may be postponed.Cytokines,glaucoma,inflammation,preoperative topical steroid,steroid eye drop,trabeculectomy
- Registration Number
- TCTR20201015003
- Lead Sponsor
- Ratchadapiseksompotch Fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 162
1. Age > 40 years old
2. Patient diagnosed with glaucoma with intraocular pressure at least 20 mmHg despite full medical treatment and plan to treat further with trabeculectomy.
3. able to understand protocol and condition to be volunteer and capable to visit to every appointment.
1. Patients with any current intraocular infection or any history of herpes epithelial keratitis
2. Patients with current steroid treatment including every route use
3. Patients with contraindication of using topical corticosteroid or Patients with history of rising intraocular pressure after apply topical corticosteroid
4. Patients with high intraocular pressure who must have trabeculectomy within 2 weeks
5. Patients with systemic disease or any contraindication that unable to have trabeculectomy
6. Patients with pregnancy or expecting pregnancy within 1 year
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Success rate of intraocular pressure reduction after trabeculectomy 12 months proportion ot success rate
- Secondary Outcome Measures
Name Time Method tear cytokine levels,relationship between tear cytokine levels and success rate 12 months Mixed model