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Study on Clinical, pathological and TCM Syndromes of IgA Nephropathy with malignant Hypertensio

Not Applicable
Recruiting
Conditions
IgAN,malignant hypertension
Registration Number
ITMCTR2200005559
Lead Sponsor
Chinese PLA General Hosptial
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Inclusion criteria (1) this study was approved by the ethics committee of the first medical center of the PLA General Hospital (ethics approval No.: s2021-165-01). The retrospective patients were exempted from signing informed consent, and the prospective patients voluntarily participated in this study and signed informed consent. (2) After 2013, patients with primary IgA nephropathy diagnosed by renal biopsy in the Department of Nephrology of the first medical center of the PLA General Hospital. (3) In hospital diagnosis of renal puncture with malignant hypertension [10], that is, the blood pressure is significantly elevated, usually > 200 / 120mmhg, and can be accompanied by significant bilateral retinopathy (flame hemorrhage, cotton wool spots or optic papilledema). (4) The age of renal biopsy was over 18 years old (including 18 years old), regardless of gender; (5) There was a questionnaire of traditional Chinese medicine within 7 days before and after renal biopsy.

Exclusion Criteria

(1) the number of evaluable glomeruli was less than 8; (2) Secondary IgA nephropathy such as purpura nephritis, lupus nephritis and hepatitis B; (3) Other renal diseases such as membranous nephropathy; (4) combined with diabetes, connective tissue disease and other systemic diseases. (5) The medical records are incomplete.

Study & Design

Study Type
Observational study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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