The effect of sensory retraining on the symptoms of patients with chemotherapy-induced sensory peripheral neuropathy

Phase 3

Conditions: Colon Cancer.
Malignant neoplasm of colon

Registration Number: IRCT20160221026674N5

Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 34

Inclusion Criteria

Age over 40 years
Reporting the presence of symptoms of peripheral neuropathy including pain, numbness, tingling and any abnormal sensations by the patient
A score of at least 4 out of 10 in at least one of the symptoms of neuropathy in the numeric rating scale of pain in the hands and feet in the last week
Completion of the chemotherapy course of patients at least 3 months and at most 9 months before the start of the study and the existence of life expectancy for at least 6 months

Exclusion Criteria

The presence of other types of peripheral neuropathy before the start of chemotherapy
The presence of any wound or swelling in the treatment area (hands and feet)
Epilepsy or cardiac arrhythmia or the presence of a pacemaker in the patient's heart
Suffering from diabetes, hyperthyroidism, kidney failure, hepatitis, AIDS and vitamin B12 deficiency
pregnancy
Use of drugs such as Gabapentin and Pregabalin by patients during the study period

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain or paresthesia intensity. Timepoint: Before the start of the intervention and 28 days and 56 days after the start of the intervention. Method of measurement: VAS.

Secondary Outcome Measures

Name	Time	Method
lnar, median and sural NCV. Timepoint: before the start of the intervention and 28 days and 56 days after the start of the intervention. Method of measurement: Electromyography device.;Hand dexterity. Timepoint: before the start of the intervention and 28 days and 56 days after the start of the intervention. Method of measurement: Purdue peg board.;Static balance. Timepoint: before the start of the intervention and 28 days and 56 days after the start of the intervention. Method of measurement: Chronometer.;Quality of life. Timepoint: before the start of the intervention and 28 days and 56 days after the start of the intervention. Method of measurement: EORTC QLQ_30 questionnare.;Lower limb function. Timepoint: before the start of the intervention and 28 days and 56 days after the start of the intervention. Method of measurement: TUG test time using chronometer.