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Clinical Trials/NCT01195649
NCT01195649
Terminated
Not Applicable

Advanced Renal Cell Carcinoma, With Failure or Unsuitable on Prior Interferon-alpha or Interleukin-2 Based Therapy

Bayer0 sites11 target enrollmentDecember 13, 2010

Overview

Phase
Not Applicable
Intervention
Sorafenib (Nexavar, BAY43-9006)
Conditions
Carcinoma, Renal Cell
Sponsor
Bayer
Enrollment
11
Primary Endpoint
Evaluation of Safety and Efficacy of treatments and average doses that are used for patients with Renal Cell Carcinoma (collection of changes in tumor status)
Status
Terminated
Last Updated
6 years ago

Overview

Brief Summary

The primary objective of this prospective, observational, post-marketing study is to evaluate the patient characteristics, pre-treatment and treatment duration in Renal Cell Carcinoma (RCC) patients who are candidates for systematic therapy and in whom a decision to treat with Nexavar® has been made under real-life practice settings and approved reimbursement restriction in Taiwan. Therefore, the main objective of the study is to collect data on:

Prescription pattern: to determine the factors affecting compliance and duration of treatment with special attention given to education status, demography, disease details, pre-treatment, concomitant medication and other baseline data

Nexavar® treatment and efficacy data

Adverse events using Common Terminology Criteria for Adverse Events (CTCAE) version 4.0

Registry
clinicaltrials.gov
Start Date
December 13, 2010
End Date
August 31, 2012
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Bayer
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients with diagnosis of advanced Renal Cell Carcinoma (RCC) and decision taken by the investigator to prescribe Nexavar® under Taiwan reimbursement guideline
  • Patients must have a life expectancy of at least 8 weeks

Exclusion Criteria

  • Exclusion criteria must follow the approved local product information.
  • Patients were lost to follow-up if no follow-up visit and no final assessment of Nexavar® was documented.

Arms & Interventions

Group 1

Intervention: Sorafenib (Nexavar, BAY43-9006)

Outcomes

Primary Outcomes

Evaluation of Safety and Efficacy of treatments and average doses that are used for patients with Renal Cell Carcinoma (collection of changes in tumor status)

Time Frame: After one year

Evaluation of Safety and Efficacy of treatments and average doses that are used for patients with Renal Cell Carcinoma (collection of number of adverse events)

Time Frame: After one year

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