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Acclimatization of Healthy Subjects During a Stay at 3200 m

Not Applicable
Completed
Conditions
Effects of High Altitude
Interventions
Other: Altitude exposure
Registration Number
NCT02451020
Lead Sponsor
University of Zurich
Brief Summary

The study evaluates respiratory acclimatization in healthy lowlanders staying for 3 weeks at 3200 m.

Detailed Description

This study evaluates the effect of 3 weeks altitude acclimatization on sleep related breathing disturbances in healthy subjects staying at 3200 m. Participants living in Bishkek, Kyrgyzstan (700 m), will be transferred by car within 4 h to the Tuja Ashu high altitude clinic (3200 m). Outcomes will be assessed repeatedly during the stay at 3200 m.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
20
Inclusion Criteria
  • Perfect health
  • Born, raised and currently living at low altitude (<800m)
  • Informed consent.
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Exclusion Criteria
  • Any acute or chronic disease
  • heavy smoking (>20 cigarettes per day).
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Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Altitude exposureAltitude exposureStay at 3200 m for 3 weeks
Primary Outcome Measures
NameTimeMethod
Mean nocturnal oxygen saturation measured by pulse oximetrynight 7 at 3200 m

Difference in mean nocturnal oxygen saturation between night 1 and night 7

Secondary Outcome Measures
NameTimeMethod
Mean nocturnal oxygen saturation measured by pulse oximetrynight 1 at 700 m (low altitude baseline)

Mean nocturnal oxygen saturation during night 1 at 700 m

Trial Locations

Locations (1)

National Center of Cardiology and Internal Medicine

🇰🇬

Bishkek, Kyrgyzstan

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