Acclimatization of Healthy Subjects During a Stay at 3200 m
- Conditions
- Effects of High Altitude
- Interventions
- Other: Altitude exposure
- Registration Number
- NCT02451020
- Lead Sponsor
- University of Zurich
- Brief Summary
The study evaluates respiratory acclimatization in healthy lowlanders staying for 3 weeks at 3200 m.
- Detailed Description
This study evaluates the effect of 3 weeks altitude acclimatization on sleep related breathing disturbances in healthy subjects staying at 3200 m. Participants living in Bishkek, Kyrgyzstan (700 m), will be transferred by car within 4 h to the Tuja Ashu high altitude clinic (3200 m). Outcomes will be assessed repeatedly during the stay at 3200 m.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
- Perfect health
- Born, raised and currently living at low altitude (<800m)
- Informed consent.
- Any acute or chronic disease
- heavy smoking (>20 cigarettes per day).
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Altitude exposure Altitude exposure Stay at 3200 m for 3 weeks
- Primary Outcome Measures
Name Time Method Mean nocturnal oxygen saturation measured by pulse oximetry night 7 at 3200 m Difference in mean nocturnal oxygen saturation between night 1 and night 7
- Secondary Outcome Measures
Name Time Method Mean nocturnal oxygen saturation measured by pulse oximetry night 1 at 700 m (low altitude baseline) Mean nocturnal oxygen saturation during night 1 at 700 m
Trial Locations
- Locations (1)
National Center of Cardiology and Internal Medicine
🇰🇬Bishkek, Kyrgyzstan