The effect of a multivitamin and mineral supplement on the common cold

Not Applicable

Completed

• Conditions: Respiratory; Common cold; Acute nasopharyngitis [common cold]

• Registration Number: ISRCTN68878070
• Lead Sponsor: Community Health Care

Brief Summary

2020 results in https://pubmed.ncbi.nlm.nih.gov/32841256/ (added 17/02/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2017-05-01
• Study Start: 2019-01-03
• Last Update Posted: 1 March 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 259

Inclusion Criteria

Aged 18 to 65 years

Exclusion Criteria

1. Planning pregnancy
2. Pregnant
3. Breastfeeding
4. Malabsorption syndromes
5. Celiac disease
6. Inflamatory bowel disease
7. Connective tissue disease
8. Immune deficiency
9. Immune suppression
10. History for intestinal surgery includiing bariatric surgery
11. Kidney disease
12. Liver disease
13. Histroy for cancer
14. History for chemotherapy
15. Utilization of disease modifying anti-rheumatoid medications or similar biologics
16. Use of proton pump inhibitors
17. Cigarette smokers

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Odds of developing an upper respiratory infection (URI) using a mixed-effects logistic regression model to account for longitudinal measurements over the 12 follow-up time points for each participant. REDCap software electronically captured all data. Participants were emailed REDCap embedded survey instruments weekly beginning the first Monday in January and for 12 consecutive weeks following during the months of January, February and March in both 2016 and 2017.<br>

Secondary Outcome Measures

Name	Time	Method
<br> Incidence, duration, and severity of specific symptoms: sore throat, headache, runny nose, cough, congestion, aches and fever.<br> Participants were emailed REDCap embedded survey instruments weekly beginning the first Monday in January and for 12 consecutive weeks following during the months of January, February and March in both 2016 and 2017. A mixed-effects logistic regression framework was utilized to assess secondary outcome measures.<br>