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Clinical Trials/NCT04266158
NCT04266158
Terminated
N/A

Functional Assistance Provided by Myoelectric Elbow-wrist- Hand Orthosis

Ohio State University1 site in 1 country28 target enrollmentOctober 1, 2017
ConditionsParesisStroke

Overview

Phase
N/A
Intervention
Not specified
Conditions
Paresis
Sponsor
Ohio State University
Enrollment
28
Locations
1
Primary Endpoint
0 - See Description
Status
Terminated
Last Updated
4 years ago

Overview

Brief Summary

The primary study objective is to compare post-stroke upper extremity (UE) movement while wearing a brace called the MyoPro 2 Motion G versus UE movement while wearing a resting splint and no device in stroke survivors with moderate UE dysfunction. During the study, subjects will undergo general training in the operation of the EMG-controlled orthosis and the comparison orthosis, and then guided through a series of standard clinical outcome measures. These outcome measures will allow the researchers to directly compare the relative benefit of the MyoPro 2 Motion G with a resting hand splint and no device in reducing UE impairment and increasing UE dexterity and functional task performance.

Registry
clinicaltrials.gov
Start Date
October 1, 2017
End Date
September 18, 2018
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Manual Muscle Test \>1/5 in the paretic biceps, triceps, finger extensors and finger flexors;
  • score \> 10 \< 30 on the Upper extremity Fugl Meyer AND active shoulder flexion of at least 30 degrees with device weight on affected arm;
  • Ability to generate consistent, detectable EMG signal from the bicep/tricep upper arm and distal forearm flexor and extensor sensor sites with wrist in neutral, and fingers in neutral. At rest, achieve an EMG of 5 or below on myConfig (wrist and fingers in neutral and elbow extended); with gain at \< 10 and boost \<12, able to reach a threshold of 10 at both bicep and wrist flexors/extensors;
  • a single stroke that is the cause of arm impairment, experienced \>12 months ago; if there are additional asymptomatic lesions (as diagnosed by MRI), these subjects may also be included. Those with another symptomatic stroke in addition to the stroke causing arm impairment are excluded;
  • score \>70 on the Modified Mini Mental Status Examination;
  • age \>18\< 85;
  • \> 6 months since previous functional or therapeutic use of an upper extremity myoelectric orthosis;
  • Height \>5'0";
  • Weight \>110\< 250 lbs.;
  • Forearm circumference (at widest part) \<13 in.;

Exclusion Criteria

  • \> 5 on a 0-10 Numeric Pain Rating Scale for pain in the paretic hand, arm or shoulder;
  • \> 3 on the Modified Ashworth Spasticity Scale in the paretic elbow, \>2 at wrist or fingers;
  • \< 2.5 on the Alexander Apraxia scale; '
  • history of neurological disorder other than stroke;
  • change in anti-spasticity medications in the last 6 months, and/or receipt of botulinum toxin in the paretic UE in the previous 4 months;
  • elbow contracture greater than 10 degrees;
  • inability to passively extend fingers while wrist is in neutral;
  • other conditions or physical/mental attributes that may undermine safety and/or full participation in the study;
  • bilateral hemiparesis.

Outcomes

Primary Outcomes

0 - See Description

Time Frame: see description above

The PI is no longer at The Ohio State University and is not actively working at another institution for record transfer. We contacted remaining study team members and department chair to obtain updates for these records. We were told the PI was dismissed and there was alleged noncompliance and misconduct. The study team and department chair are unable to confirm if available documents for these records are accurate.

Study Sites (1)

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