NL-OMON41322已完成不适用
Tryptophan depletion in Parkinson*s disease patients treated with deep brain stimulation of the subthalamic nucleus: effects on mood and motor functions. - Tryptophan depletion in PD patients treated with STN DBS.
Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 30 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Subjects must be mentally competent (*wilsbekwaam*)
- •Subjects must have undergone STN DBS surgery for Parkinson's disease symptomatology ;Age, duration and severity of disease, duration of DBS implantation do not play a role in the selection process.
排除标准
- •Head injury
- •Neurological disorders other than PD
- •Psychoactive medication: antidepressants and antipsychotics (a stable dose of benzodiazepines will be allowed).
- •Clinically relevant cognitive decline, operationalized as an Mini Mental State Examination score <24
- •Current psychiatric symptomatology, operationalized as a Hamilton Depression scale score >16 or a score >2 on any of the MDS-UPDRS section I items.
- •Current malignancy or infection;Age, duration and severity of disease, duration of DBS implantation do not play a role in the selection process.
研究者
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