Trends in allogeneic hematopoietic cell transplantation for adult ALL over the past three decades
Not Applicable
- Conditions
- Acute lymphoblastic leukemia
- Registration Number
- JPRN-UMIN000047159
- Lead Sponsor
- agoya University Hospital
- Brief Summary
Allo-HCT outcomes for adults with ALL have improved over the past 30 years. Non-relapse mortality was improved regardless of Philadelphia chromosome (Ph) status and disease status. Although there were continual improvements in adjusted survival for Ph-positive patients, the improvement was inadequate for Ph- patients with t(4;11), t(8;14), t(14;18), or hypodiploidy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 8467
Inclusion Criteria
Not provided
Exclusion Criteria
Patients who did not agree to participate in this study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Survival according to disease stage and transplant periods
- Secondary Outcome Measures
Name Time Method 1. Relapse rate and non-relapse mortality according to disease stage and transplant periods 2. Risk factors for survival, relapse, or non-relapse mortality