Alcohol Use Disorders (AUDs) and Post-traumatic Stress Disorder (PTSD) Treatment for Victims of Partner Violence

Phase 2

Completed

• Conditions: PTSD; Substance Use Disorders
• Interventions: Behavioral: Integrated psychotherapy for PTSD and substance use; Behavioral: 12-step based supportive therapy

• Registration Number: NCT00607412
• Lead Sponsor: University of California, San Diego

Brief Summary

The goal of this study is to evaluate a psychotherapy for PTSD and substance use disorders among women who have experienced domestic violence. The hypothesis is that women who receive present-focused, integrated treatment will have greater PTSD symptom reduction and have less substance use after treatment than women in the control condition who will receive supportive therapy based on a 12-step approach.

Detailed Description

The goal of this study is to evaluate an integrated psychotherapy for PTSD and substance use disorders among female victims of intimate partner violence. The hypothesis is that women who receive present-focused, integrated treatment will have greater PTSD symptom reduction and have less substance use post-treatment than women in the control condition who will receive supportive therapy based on a 12-step approach.

Study Timeline

• Study Start: 2007-08
• Study First Submitted: 2007-12-26
• Study First Submitted QC: 2008-01-22
• Study First Posted: 2008-02-05
• Status Verified: 2009-06
• Primary Completion: 2011-05
• Study Completion: 2011-05
• Last Update Submitted: 2011-05-10
• Last Update Posted: 2011-05-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

• female victims of partner violence
• at least one month out of the abusive relationship
• meet DSM-IV (American Psychiatric Association, 1994) criteria for PTSD and an alcohol use disorder
• literate in English
• have not changed psychotropic medications or dosages within the past two months and agree not to during the active phase (first 12 weeks) of the intervention
• have an identified primary care physician

Exclusion Criteria

• moderate or severe cognitive impairment as measured by a Mini-Mental State Examination score less than or equal to 18
• Histories of psychosis or mania may be excluded because the presence of these disorders is thought to impede progress in psychotherapy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Integrated psychotherapy for PTSD and substance use	Present focused, integrated psychotherapy for PTSD and substance use disorders
2	12-step based supportive therapy	Supportive therapy using 12-step model

Primary Outcome Measures

Name	Time	Method
CAPS for PTSD symptoms and ASI for substance use	pre, mid treatment, post, 3-month follow-up, 6-month follow-up

Secondary Outcome Measures

Name	Time	Method
Timeline Follow-back procedure, Beck Depression Inventory	same as primary

Trial Locations

Locations (1)

UCSD Outpatient Psychiatry; 🇺🇸 San Diego, California, United States