Quantitative Sensory Testing, Physical Activity, and Body Composition in Adults
试验速览
- 阶段
- 不适用
- 入组人数
- 250
- 试验地点
- 2
- 主要终点
- The change from baseline of pain ratings during temporal summation of pressure pain assessment
研究概览
简要总结
The purpose of this study is to investigate the influence of baseline experimental pain sensitivity and expectation on the pain response following a single exercise session. Pain assessment will be done with different intensities of noxious stimuli. In addition, the expectation of how exercise impacts pain will be studied.
详细描述
The relation between baseline pain sensitivity and the pain response following exercise is not clear. The aims of this study are to investigate the influence of baseline experimental pain sensitivity on the pain response following submaximal isometric exercise, and whether expectations would influence outcomes with subsequent exposure to exercise.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
Participants are blinded to the hypothesis of this study.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy adults
- •English proficiency
排除标准
- •Acute pain condition
- •Chronic pain condition
- •Mental health disorder
- •Cardiovascular disease
- •Any chronic illness
- •Difficulty with physical exercise
- •Recent surgery
- •Pulmonary disease
- •Raynaud disease
- •Claustrophobia
研究组 & 干预措施
submaximal isometric exercise.
submaximal isometric exercise will be performed.
干预措施: Submaximal isometric exercise (Other)
Quiet rest.
Subject will rest in seating position for a period that mimics the exercise time.
结局指标
主要结局
The change from baseline of pain ratings during temporal summation of pressure pain assessment
时间窗: Before and immediately after exercise or quiet rest in session 1 and session 2 which will be on day 1 and day 7 of data collection.
Temporal summation is the increase of pain over time caused by a constant or repetitive noxious stimulus. Pain reports will be obtained during the application of constant mechanical stimulus with various intensities. Subjects will be asked to rate the pain using a numerical pain rating scale that ranges from 0 (no pain) to 10 (worst pain). Pain ratings will be obtained at the beginning, during, and at the end of the test while a noxious stimulus is applied to the index finger. The change of pain ratings relative to baseline after exercise or quiet rest will be assessed.
次要结局
- State version of the State-Trait Anxiety Inventory (STAI)(After each temporal summation protocol in the first and second session which are on day 1 and day 7 of data collection.)
- Expectation(Before exercise which will be on day 1 and day 7 of data collection.)
- Fat mass assessment using Dual-energy x-ray absorptiometry.(Baseline (in the first or second session) which is either day 1 or day 7 of data collection.)
- Trait version of the State-Trait Anxiety Inventory (STAI)(Baseline (beginning of session 1) which is day 1 of the data collection.)
- Pain catastrophizing scale(Baseline (beginning of session 1) which is day 1 of the data collection.)
- Muscle mass assessment using Dual-energy x-ray absorptiometry.(Baseline (in the first or second session) which is either day 1 or day 7 of data collection.)
- Situational pain catastrophizing scale(After each temporal summation protocol in the first and second session which are day 1 and day 7 of data collection.)
- Physical activity assessment using International physical activity questionnaire.(Baseline (beginning of session 1 or 2) which is either day 1 or day 7 of data collection.)