Quantitative Sensory Testing, Physical Activity, and Body Composition in Adults
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Healthy Subjects
- Sponsor
- Marquette University
- Enrollment
- 250
- Locations
- 1
- Primary Endpoint
- The change from baseline of pain ratings during temporal summation of pressure pain assessment
- Last Updated
- 7 years ago
Overview
Brief Summary
The purpose of this study is to investigate the influence of baseline experimental pain sensitivity and expectation on the pain response following a single exercise session. Pain assessment will be done with different intensities of noxious stimuli. In addition, the expectation of how exercise impacts pain will be studied.
Detailed Description
The relation between baseline pain sensitivity and the pain response following exercise is not clear. The aims of this study are to investigate the influence of baseline experimental pain sensitivity on the pain response following submaximal isometric exercise, and whether expectations would influence outcomes with subsequent exposure to exercise.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Healthy adults
- •English proficiency
Exclusion Criteria
- •Acute pain condition
- •Chronic pain condition
- •Mental health disorder
- •Cardiovascular disease
- •Any chronic illness
- •Difficulty with physical exercise
- •Recent surgery
- •Pulmonary disease
- •Raynaud disease
- •Claustrophobia
Outcomes
Primary Outcomes
The change from baseline of pain ratings during temporal summation of pressure pain assessment
Time Frame: Before and immediately after exercise or quiet rest in session 1 and session 2 which will be on day 1 and day 7 of data collection.
Temporal summation is the increase of pain over time caused by a constant or repetitive noxious stimulus. Pain reports will be obtained during the application of constant mechanical stimulus with various intensities. Subjects will be asked to rate the pain using a numerical pain rating scale that ranges from 0 (no pain) to 10 (worst pain). Pain ratings will be obtained at the beginning, during, and at the end of the test while a noxious stimulus is applied to the index finger. The change of pain ratings relative to baseline after exercise or quiet rest will be assessed.
Secondary Outcomes
- State version of the State-Trait Anxiety Inventory (STAI)(After each temporal summation protocol in the first and second session which are on day 1 and day 7 of data collection.)
- Expectation(Before exercise which will be on day 1 and day 7 of data collection.)
- Fat mass assessment using Dual-energy x-ray absorptiometry.(Baseline (in the first or second session) which is either day 1 or day 7 of data collection.)
- Trait version of the State-Trait Anxiety Inventory (STAI)(Baseline (beginning of session 1) which is day 1 of the data collection.)
- Pain catastrophizing scale(Baseline (beginning of session 1) which is day 1 of the data collection.)
- Muscle mass assessment using Dual-energy x-ray absorptiometry.(Baseline (in the first or second session) which is either day 1 or day 7 of data collection.)
- Situational pain catastrophizing scale(After each temporal summation protocol in the first and second session which are day 1 and day 7 of data collection.)
- Physical activity assessment using International physical activity questionnaire.(Baseline (beginning of session 1 or 2) which is either day 1 or day 7 of data collection.)