Towards an integrated self-monitoring solution for stroke/TIA: the BP:Together study

niversity of Oxford0 个研究点目标入组 610 人开始时间: 2019年9月6日最近更新: 2023年1月30日

适应症

试验速览

2023 Interim results article in https://pubmed.ncbi.nlm.nih.gov/36639797/ Feasibility results (added 16/01/2023)

•1. Participant is willing and able to give informed consent for participation in the study
•2. Male or female, aged 18 years or above
•3. Previous history of stroke and/or specialist confirmed TIA at least one month before randomisation
•4. Baseline systolic blood pressure > 130mmHg (mean of 2nd and 3rd readings)
•5. Willing and able to comply with all study procedures

•1. Diagnosis of dementia (Clinical Code)
•2. Score over 10 on the short orientation memory concentration test
•3. Any other significant disease or disorder which, in the opinion of the Investigator, may put the participants at risk because of participation in the trial
•4. Pregnancy
•5. BP > 180/110mmHg at baseline (to be referred to GP but could be subsequently rescreened if < 180/110mmHg)
•6. More than three antihypertensives
•7. Unwilling to self-monitor
•8. Receiving care for blood pressure by a specialist rather than a primary care physician
•9. Stage 4 CKD or worse – i.e.: eGFR less than 30 mL/min/1.73 m2 (as these persons are more likely to be managed by specialists, are more prone to Acute Kidney Injury and/or hyperkalemia and less responsive to certain antihypertensives?)
•10. Diagnosed atrial fibrillation
•11. Orthostatic hypotension: more than 20mmHg systolic drop after standing for 1 minute. Not relevant if participant unable to stand
•12. Participation in other studies that concern hypertension and/or adjustment of antihypertensive medication

发起方