Registry of Patients With Chronic Thromboembolic Pulmonary Hypertension in Novosibirsk Region

• Conditions: Chronic Thromboembolic Pulmonary Hypertension

• Registration Number: NCT03349164
• Lead Sponsor: Novosibirsk Scientific Research Institute for Circulatory Pathology

Brief Summary

There will be assessment of patients after acute pulmonary embolism for the development of CTEPH

Detailed Description

There will be assessment of patients after acute pulmonary embolism for the development of CTEPH.

There will be analysis of case histories of 40 patients with acute pulmonary embolism. All this patients will be clinically assessed by local cardiologist. Also echocardiography, lung VQ scans (perfusion and ventilation) will be performed.

Patients with chronic thromboembolic pulmonary hypertension will be assessed by local team experienced in CTEPH treatment.

Study Timeline

• Study Start: 2017-01-01
• Status Verified: 2017-11
• Primary Completion: 2017-11-10
• Study First Submitted: 2017-11-12
• Study First Submitted QC: 2017-11-18
• Last Update Submitted: 2017-11-18
• Study First Posted: 2017-11-21
• Last Update Posted: 2017-11-21
• Study Completion: 2018-03-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• patients who had episodes of acute pulmonary embolism
• 3-4 months of anticoagulation treatment after acute pulmonary embolism
• informed consent

Exclusion Criteria

• pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
clinical presentation of chronic thromboembolic pulmonary hypertension	3-4 month after acute pulmonary embolism	clinical assessment of physical capacity of patient with 6 minute walking distance test and NYHA functional class

Secondary Outcome Measures

Name	Time	Method
presence of pulmonary hypertension - mean pulmonary artery pressure > 25 mm Hg according to echocardiography	3-4 month after acute pulmonary embolism	presence of pulmonary hypertension - mean pulmonary artery pressure \> 25 mm Hg according to echocardiography
presence of perfusion deficit in pulmonary artery according to VQ scan	3-4 month after acute pulmonary embolism	presence of perfusion deficit in pulmonary artery according to VQ scan

Trial Locations

Locations (1)

Novosibirsk research institute of circulation pathology; 🇷🇺 Novosibirsk, Novosibirskaya Oblast', Russian Federation