Safety and feasibility of selective dorsal rhizotomy in patients with spinal cord injury-induced spasticity

Shahid Beheshti University of Medical Sciences0 个研究点目标入组 15 人开始时间: 待定最近更新: 2022年5月2日

试验速览

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•Modified Ashworth scale (MAS) of at least 3 and spasm frequency score (SFS) of at least 2
•Patients with intractable spasticity after at least 6 months therapy with oral antispasmodic agents
•Candidates for intrathecal baclofen infusion who could not receive this therapy
•Age greater than 18 years
•Complete spinal cord injury or American Spinal Injury Association impairment scale (AIS) grade A
•Written informed consent obtained from the patient

•Any brain lesion in areas involved in coordination or posture, such as basal ganglia or cerebellum based on MR imaging
•Any form of movement disorders, such as dyskinesia, dystonia, or ataxia
•Concurrent traumatic brain injury
•Genetic etiology for spasticity, such as hereditary spastic paraplegia
•Any evidence of a progressive neurological disorder
•Treatment with oral antispasmodic agents for less than six months
•Prior therapy with intrathecal baclofen pump
•Pregnancy or lactation
•Participation in another study during the present study period

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