ISRCTN14611625已完成3 期
Prophylactic effects of ibuprofen vs placebo on cerebral vasospasm following aneurysmal subarachnoid hemorrhage: a single-center randomized, controlled pilot trial
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 30
研究概览
简要总结
2022 Protocol article in https://pubmed.ncbi.nlm.nih.gov/35414560/ (added 06/09/2023)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Aneurysmal subarachnoid hemorrhage verified by a brain CT scan
- •2. Older than 18 years old
- •3. Admitted less than 6 hours after the onset of clinical symptoms
- •4. World Federation of Neurological Surgeons (WFNS) score I, II and III at admission
排除标准
- •1. Patients who have hypersensitivity to aspirin, ibuprofen or other NSAIDs
- •2. Previous and prolonged use of any type of NSAIDs other than aspirin
- •3. History of aneurysmal re-bleeding, and active bleeding of a gastrointestinal ulcer, hemodynamic instability, and pregnancy
- •4. Patients with a history of myocardial infarction(MI) or percutaneous coronary interventions
研究者
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