Investigating the effect of vaginal washing before Misoprostol insertion on ripening cervix before labor inductio

Phase 3

Recruiting

Conditions: abor induction.
Other failed induction of labour
O61.8

Registration Number: IRCT20080826001096N7

Lead Sponsor: Research vice-chancellorship, Guilan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Female

Target Recruitment: 164

Inclusion Criteria

pregnant women ages 18 to 40
Having 38 to 40 week pregnancy
Having singleton pregnancy
Having normal fetal heart rate (FHR)
Having cephalic presentation
Not having a ban on normal vaginal delivery (cephalopelvic disproportion)
Having no uterine contractions spontaneously and effectively (less than three contractions in 30 minutes)
Having a Bishop score of less than 6
Estimation of fetal weight less than 4000 grams
Candidates for termination of pregnancy (post-term pregnancy (42 weeks and more), oligohydramnios, decreased fetal movements, abdominal biophysical profile score, maternal diabetes mellitus, intrauterine growth retardation, and preeclampsia)

Exclusion Criteria

Having sensitivity to known prostaglandin (with questions like skin manifestations, hives and rash, dyspnea and coughing, chest pain and blurred vision after taking prostaglandin)
Having vaginal bleeding
Preterm rupture of membranes
Having a history of previous cesarean section or scar on the uterus
Having fetal anomaly
Having doubts about Chorioamnionitis

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Success of labor induction. Timepoint: Post-partum. Method of measurement: Duration from induction to active phase of labor.

Secondary Outcome Measures

Name	Time	Method
The duration of vaginal Misoprostol to successful labor induction. Timepoint: During labor. Method of measurement: hour.;Vaginal PH. Timepoint: Before and after vaginal washing. Method of measurement: Nitrazine paper.;Duration from induction to end of first stage of labor. Timepoint: During labor until the end of the first stage of labor. Method of measurement: hour.;Duration from induction to active phase of labor. Timepoint: During labor until the active phase of labor. Method of measurement: hour.;Maternal complications (tachysystole, hyperstimulation, etc.). Timepoint: During labor. Method of measurement: Patient complaint.;Neonatal complications include meconium excretion, Apgar score less than 7, admission to the NICU. Timepoint: During labor until after delivery. Method of measurement: Observations by doctor.