Preoperative Optimization of the High-Risk Patient undergoing Hip Fracture Surgery - Hip-Op

• Conditions: Patients with elevated NT-proBNP as a sign of left ventricular dysfunction undergoing hipfracturesurgery.; MedDRA version: 12.1Level: PTClassification code 10020100Term: Hip fracture; MedDRA version: 12.1Level: HLTClassification code 10019283Term: Heart failure signs and symptoms

• Registration Number: EUCTR2010-022816-38-SE
• Lead Sponsor: Department of Anesthesiology & Intensive Care

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-10-26
• Last Update Posted: 21 August 2012

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: All
• Target Recruitment: 0

Inclusion Criteria

Inclusions Criteria:
1.Patients >= 65 yrs
2.Proximal femur fracture where the patient is planned to be operated during the day (Monday-Friday).
3.NT-proBNP > 900 ng/l in patients 65-75 yrs old, and >1800 ng/l in patients > 75 yrs.
4.Informed consent provided by the patient.

All of the above criteria must be fulfilled before the patient can be included in the study.

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Exclusions Criteria:

1.Informed consent cannot be provided
2.Mental or verbal difficulty in understanding or expressing willingness to participate in the study.
3.Instable angina pectoris.
4.Ongoing myocardial infarct or ischemia
5.Circulatory shock
6.Decompensated cardiac failure or pulmonary oedema
7.Pathologic femur fracture
8.Chronic haemodialysis
9.Cardiac valve incompetence that has haemodynamic consequences

Any one of the above is a criterion for exclusion.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified