Rapid Administration of iron Polymaltose whilst In the operating Department for patients with iron deficiencyThe RAPID Study

Phase 4

Completed

• Conditions: Blood - Other blood disorders; Iron deficiency; Blood - Anaemia

• Registration Number: ACTRN12613000356763
• Lead Sponsor: Dr Roger M Browning

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-04-04
• Last Update Posted: 5 January 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Female Hb < 120 g/L and ferritin < 100
Male Hb < 130 g/L and ferritin < 100
Iron deficiency alone ferritin < 30
Undergoing general anaesthesia for a procedure

Exclusion Criteria

- Pregnancy
- Iron overload (haemochromatosis or haemosiderosis) or ferritin > 100
- Clinically significant renal or liver disease
- Chronic polyarthritis
- Active infection
- Allergy / intolerance to iron polymaltose

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The proportion of patients with systolic BP less than 80mmHg during iron infusion compoared to the proportion of patients with systolic BP less than 80mmHg in the first 15 min after induction of anaesthesia. Statistical comparison using fishers exact test.[First 15 min after induction of anaesthesia compared to 30min period around iron infusion (15min during and 15min after)]

Secondary Outcome Measures

Name	Time	Method
Absolute difference in systolic blood pressure change during iron infusion compared to after induction of anaesthesia. Statistical analysis using t-test to compare measured difference.[First 15 min after induction of anaesthesia compared to 30min period around iron infusion (15min during and 15min after)]