Ultrasound-guided Axillary Vein Catheterization in Trauma

Recruiting

• Conditions: Multiple Trauma/Injuries

• Registration Number: NCT05896735
• Lead Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Brief Summary

It is very important to choose the best central venous catheterization route for trauma patients, the determinants that need to be considered comprehensively include coagulation dysfunction, fracture of the clavicle on the side of the puncture, and tracheotomy care. More importantly, whether it can used simultaneously for accurate volume and invasive hemodynamic monitoring. For the purpose of support of cardiopulmonary function, the ideal position of the catheter tip is vital with regard to an accurate CVP and hemodynamic monitoring. Cannulation of the axillary vein is ideal for patients with severe poly-trauma because it avoids the thoracic cavity, intercostal arteries, tracheostomy, and clavicle, and is prone to compression even if the artery is injured. At present, there is no systematic introduction of ultrasound-guided axillary vein catheterization in the trauma ICU in the literature. Since Oct 2021, the investigators have attempted to practice axillary vein catheterization for this crucial trauma population; unfortunately, the investigators have not know till now whether this procedure is associated with accurate tip placement and its safety should also be weighted. So it is necessary to summarize the relevant clinical data.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-04
• Study Start: 2023-04-25
• Study First Submitted: 2023-05-02
• Study First Submitted QC: 2023-05-31
• Study First Posted: 2023-06-09
• Last Update Submitted: 2023-06-12
• Last Update Posted: 2023-06-13
• Primary Completion: 2023-07-31
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 132

Inclusion Criteria

• Trauma patients admitted to TICU
• Receiving axillary vein catheterization during TICU stay

Exclusion Criteria

• Without record of axillary vein catheterization
• Without imaging confirming （X-ray or chest CT） the location of catheter tip

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Accurate placement of the CVC catheter tip for measuring CVP or invasive hemodynamic monitoring	2021-10-1~2023-04-30	Placement of the CVC catheter tip between level of tracheal carina and within 2 cm downward is ideal for measuring CVP or invasive hemodynamic monitoring.

Secondary Outcome Measures

Name	Time	Method
Thromboembolism events	2021-10-1~2023-04-30	Incidents of thromboembolism events after axillary vein catheterization during TICU stay
TICU mortality	2021-10-1~2023-04-30	Death rate during TICU stay
Puncture complications after axillary vein catheterization	2021-10-1~2023-04-30	Pneumothorax, thrombus, artery injury, local infection, catheter-related infection
TICU length of stay	2021-10-1~2023-04-30	Time (d) spent during TICU therapy
Ventilator support	2021-10-1~2023-04-30	Duration of ventilator support during TICU stay

Trial Locations

Locations (1)

2 nd Affiliated Hospital, School of Medicine, Zhejiang University, China; 🇨🇳 Hangzhou, Zhejiang, China