Pre-operative Versus Post-operative Vaginal Cleansing With Chlorhexidine Solution in Prevention Post-Cesarean Section Infection
- Conditions
- Post Cesarean Infectious Morbidity
- Interventions
- Procedure: Chlorhexidine
- Registration Number
- NCT06176573
- Lead Sponsor
- Federal Teaching Hospital Abakaliki
- Brief Summary
Maternal infectious morbidity is a common complication of cesarean delivery, especially in a poor recourse setting like ours. This study was done to compare the effectiveness of preoperative vaginal cleansing with immediate postoperative vaginal cleansing with chlorhexidine solution in preventing post-cesarean infectious morbidities. Randomized trial involving 120 consented women who had elective or emergency cesarean sections at term, 60 in each group. Group 1 had preoperative while group 2 had postoperative vaginal cleansing with 1% chlorhexidine.
- Detailed Description
Background: Maternal infectious morbidity is a common complication of cesarean delivery, especially in a poor recourse setting like ours. This study was done in a tertiary hospital in Abakaliki, Ebonyi State, Southeast Nigeria over a period of 5 months. The State is inhabited mainly by rural farmers and petty traders. Literacy is low and poverty is common with poor maternal health indices.
Aim: To compare the effectiveness of preoperative vaginal cleansing with immediate postoperative vaginal cleansing with chlorhexidine solution in preventing post-cesarean infectious morbidities.
Method: Randomized trial involving 120 consented women who had elective or emergency cesarean sections at term, 60 in each group. Group 1 had preoperative while group 2 had postoperative vaginal cleansing with 1% chlorhexidine. Research Randomizer software was used to generate 120 numbers. Sixty numbers were randomly generated from a pool of 120 numbers and were assigned to group 1 while the remaining 60 numbers were automatically assigned to group 2. Both groups received antibiotics and anterior abdominal wall scrubbing. There were monitored for symptoms and signs of endometritis, wound infection and pyrexia till discharge.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 120
- Those that gave consent
- Term pregnancy
- Refusal of consent
- Antepartum hemorrhage
- Cord prolapse
- Fetal distress
- Anemia in pregnancy
- Presence of fever and chorioamnionitis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description First arm - Pre-operative vaginal cleansing with chlorhexidine Chlorhexidine Had vaginal cleansing with chlorhexidine prior to cesarean section and were monitored for infectious morbidity. Second arm - Post-operative vaginal cleansing with chlorhexidine Chlorhexidine Had vaginal cleansing with chlorhexidine after cesarean section and were monitored for infectious morbidity.
- Primary Outcome Measures
Name Time Method infectious morbidity six (6) weeks. development of infectious morbidity following cesarean section after vaginal cleansing.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Alex Ekwueme Federal University Teaching Hospital
🇳🇬Abakaliki, Ebonyi, Nigeria