Comparison of symptoms, side effects and functional impairment in ADHD patients treated with methylphenidate (MPH) twice daily versus three times daily
Not Applicable
- Conditions
- ADHDADHD,Methyphenidate,MPH,attention-deficit hyperactivity disorder
- Registration Number
- TCTR20190915002
- Lead Sponsor
- faculty of medicine siriraj hospital mahidol university, Thailand
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
1.New case diagnosis of ADHD by DSM-5 criteria age between 6 years to 17 years 11 months at Child psychiatry department, Siriraj Hospital
2.Patient never used methylphenidate before.
3.Caregiver knowns the patient more than 6 months.
Exclusion Criteria
1. History of methylphenidate allergy.
2. Patient with bipolar disorder, psychotic disorder, autism spectrum disorder, major depressive disorder or intellectual disability
3. The child psychitist prescribed for long acting methylphenidate ex. Concerta
4. Patient who have Heart diease, epilepsy, HT, Tics
5. Patient who got medicine which drug interaction with methylphenidate.
6. Patient who got psychiatric drugs which decrease efficacy of methylphenidate ex. risperidone, clonidine
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method symptoms reduction evaluation of Hyperactive, impulsivity and inattentive symptoms by THASS Wk0,6,10,14 Intention-to-treat (ITT) analysis,multiple imputation,t-test ,Chi-square test ,functional impairment evalation by WEISS Functional Impairment Rating Scale Report Wk0,6,10,14 Intention-to-treat (ITT) analysis,multiple imputation,t-test ,Chi-square test
- Secondary Outcome Measures
Name Time Method Side effect Wk0,6,10,14 Intention-to-treat (ITT) analysis,multiple imputation,t-test ,Chi-square test