The Effect of a Mobile Application on Enhancing Pulmonary Rehabilitation After Lung Cancer Surgery
- Conditions
- Pulmonary RehabilitationTelerehabilitationLung Cancer
- Interventions
- Behavioral: RehabLung mobile applicationBehavioral: Lung cancer postoperative standard careOther: Healthcare interactive Web Platform
- Registration Number
- NCT06600503
- Lead Sponsor
- National Cheng Kung University
- Brief Summary
The goal of this clinical trial is to investigate the effect of a mobile application intervention on postoperative lung rehabilitation. The main purposes of this study are:
1. To understand the effectiveness of the pulmonary rehabilitation mobile application in improving lung function.
2. To assess the feasibility of the pulmonary rehabilitation mobile application in post-surgery rehabilitation care.
Researchers will compare the intervention group (using the pulmonary rehabilitation mobile application) to the usual care group to determine if the mobile application is effective in lung surgery rehabilitation.
Participants will join the study immediately after providing informed consent and will continue for up to 7 weeks post-surgery. Participants will be randomly allocated to either the intervention group or the control group. Both groups will receive regular pulmonary rehabilitation during their hospital stay (1 day before surgery and 2 to 3 days after surgery). Researchers will guide participants in the intervention group to use the mobile application for pulmonary rehabilitation exercises throughout the study period. Participants in the usual care group will receive health education and an exercise guide before discharge. Participants will undergo three study assessments: at baseline (within 1 week after enrollment), post-surgery (week 5), and at follow-up (week 8).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 36
- age over 20 years
- primary diagnosis of lung cancer at any stage and type
- referral to lung cancer resection by thoracotomy or videothoracoscopy
- ability to understand and consent to the trial procedures
- conscious and cognition intact
- included adjuvant treatments (chemotherapy or radiotherapy)
- previous history of thoracic surgery
- neurological and/or musculoskeletal comorbidities
- visual or hearing impairment
- acute respiratory illness
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description application inttervention group RehabLung mobile application The experimental group will receive standard postoperative care, including chest rehabilitation, a mobile application for remote self-training every day after surgery, and an interactive healthcare web platform for health education. application inttervention group Healthcare interactive Web Platform The experimental group will receive standard postoperative care, including chest rehabilitation, a mobile application for remote self-training every day after surgery, and an interactive healthcare web platform for health education. Usual care group Lung cancer postoperative standard care The usual care group will receive standard postoperative care, including chest rehabilitation and an interactive healthcare web platform for health education Usual care group Healthcare interactive Web Platform The usual care group will receive standard postoperative care, including chest rehabilitation and an interactive healthcare web platform for health education
- Primary Outcome Measures
Name Time Method Exercise capacity-oxygen consumption Baseline, post-surgery assessment at week 5, follow-up assessment at week 8 Cardiorespiratory fitness is evaluated by a cardiopulmonary exercise test using a cycle ergometer. Participants will be encouraged to perform a cycle ergometer stress test to assess their cardiopulmonary function. During the test, the workload will gradually increase by 10 watts per minute until the participant reaches peak exercise capacity. Throughout the exercise test, participants will be carefully monitored for echocardiography and heart rate, and will wear a mask to analyze ventilatory outcomes using a computed gas analysis system. Peak oxygen consumption (VO2 peak) will be measured during the exercise test, and values for the difference and change in percent predicted (peak oxygen uptake \[mL/kg/min\], VO2 peak difference \[mL/kg/min\], VO2 peak change \[%\], and \[% predicted\]) will be obtained from gas analysis. The predicted values will be referenced from the system based on race, age, height, biological sex, and weight.
Exercise capacity-workload Baseline, post-surgery assessment at week 5, follow-up assessment at week 8 Cardiorespiratory fitness is evaluated by a cardiopulmonary exercise test using a cycle ergometer. Participants will be encouraged to perform a cycle ergometer stress test to assess their cardiopulmonary function. During the test, the workload will gradually increase by 10 watts per minute until the participant reaches peak exercise capacity. Throughout the exercise test, participants will be carefully monitored for echocardiography and heart rate, and will wear a mask to analyze ventilatory outcomes using a computed gas analysis system.
The workload achieved during exercise test will be recored by peak work rate (watts), and peak work rate (%pred.) The predicted workload will be referenced from the system based on race, age, height, biological sex, and weight.Exercise capacity-ventilatory efficiency Baseline, post-surgery assessment at week 5, follow-up assessment at week 8 Cardiorespiratory fitness is evaluated by a cardiopulmonary exercise test using a cycle ergometer. Participants will be encouraged to perform a cycle ergometer stress test to assess their cardiopulmonary function. During the test, the workload will gradually increase by 10 watts per minute until the participant reaches peak exercise capacity. Throughout the exercise test, participants will be carefully monitored for echocardiography and heart rate, and will wear a mask to analyze ventilatory outcomes using a computed gas analysis system.
The gas analysis of oxygen exchange efficiency includes maximal ventilation (L/min), maximal ventilation (% predicted), ventilatory equivalents slope, VE/VCO2 slope, ventilatory equivalents, and VE/VCO2 (% predicted).Exercise capacity-Anaerobic threshold Baseline, post-surgery assessment at week 5, follow-up assessment at week 8 Cardiorespiratory fitness is evaluated by a cardiopulmonary exercise test using a cycle ergometer. Participants will be encouraged to perform a cycle ergometer stress test to assess their cardiopulmonary function. During the test, the workload will gradually increase by 10 watts per minute until the participant reaches peak exercise capacity. Throughout the exercise test, participants will be carefully monitored for echocardiography and heart rate, and will wear a mask to analyze ventilatory outcomes using a computed gas analysis system.
Anaerobic threshold (AT) (mL/kg/min) is defined as a nonlinear increase in CO2 production, which will be analyze during gas analysis in an incremental exercise test.Pulmoanry function Baseline, post-surgery assessment at week 5, follow-up assessment at week 8 The pulmonary function test, assessed by spirometry, is performed to evaluate lung volumes over time and ventilatory capacity. Participants will be guided by experienced therapists to take a maximal inspiration, then exhale with maximal effort for as long and as fast as possible. Measurements include forced vital capacity (FVC \[L, % predicted\]), forced expiratory volume in one second (FEV1 \[L, % predicted\]), and the ratio of the two volumes (FEV1/FVC \[% predicted\]). The predicted values will be referenced from large population studies of healthy adults, matched by race, age, height, biological sex, and weight.
- Secondary Outcome Measures
Name Time Method Global respiratory muscle strength Baseline, post-surgery assessment at week 5, follow-up assessment at week 8 Global respiratory muscle strength is assessed using a pressure gauge and a mouthpiece. Participants are guided to perform maximal exhalation followed by full inhalation, and then maximal inhalation followed by full exhalation through the mouth. Measurements include maximal inspiratory pressure (PImax \[cmH2O, % predicted\]) and maximal expiratory pressure (PEmax \[cmH2O, % predicted\]).
Six Minute Walk Test, 6MWT Baseline, post-surgery assessment at week 5, follow-up assessment at week 8 The six-minute walk test is conducted by having a therapist encourage the participant to walk continuously at a comfortable speed for six minutes. The distance covered during the six-minute walk test (m) will be recorded. Throughout the test, vital signs will be carefully monitored.
Postoperative pulmonary complications Baseline, post-surgery assessment at week 5, follow-up assessment at week 8 Postoperative pulmonary complications (PPCs) will be recorded from medical records including atelectasis, pneumothorax, respiratory infection, respiratory failure, pleural effusion, bronchospasm, aspiration pneumonitis, acute respiratory distress syndrome,
Quality of life - EORTC QLQ-C30 Baseline, post-surgery assessment at week 5, follow-up assessment at week 8 Quality of life specific to lung cancer patients is assessed using the EORTC QLQ-C30 (European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30). This questionnaire evaluates various aspects of quality of life, including physical, role, cognitive, emotional, and social functioning, as well as cancer-related symptoms and overall health status. Scores range from 0 to 100 across the 30 items. A higher score on the global scale indicates a better quality of life.
Qulaity of life-WHOQOL-BREF Baseline, post-surgery assessment at week 5, follow-up assessment at week 8 The measurement of quality of life in participants is assessed using the WHOQOL-BREF questionnaire (World Health Organization Quality of Life Brief Version). This questionnaire includes 26 items that assess perceptions of quality of life across physical, psychological, social, and environmental domains, with scores ranging from 0 to 100. Higher scores indicate better quality of life.