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Clinical Trials/NCT01725074
NCT01725074
Unknown
N/A

Koronare Herzkrankheit Projekt Mannheim

Genossenschaft Gesundheitsprojekt Mannheim e.G1 site in 1 country320 target enrollmentJuly 2011

Overview

Phase
N/A
Intervention
Not specified
Conditions
Coronary Heart Disease
Sponsor
Genossenschaft Gesundheitsprojekt Mannheim e.G
Enrollment
320
Locations
1
Primary Endpoint
Change in health outcomes
Last Updated
13 years ago

Overview

Brief Summary

This randomized controlled trial (RCT) will examine a case management program for patients suffering from coronary heart disease with multimorbidity in Mannheim, Germany. The trail consists of 3 treatment arms: 1) intensified case management; 2) social interaction alone 3) standard care. The main objectives are to evaluate how case management and social interaction alone compared to standard medical care affect the primary and secondary outcomes: physical health, quality of life, loneliness, depression, self-efficacy, outcome expectancies, social support, health locus of control, lifestyle behavior, social network, vulnerability, intention, severity, health worries and cognitive functions.

Detailed Description

This randomized controlled trial (RCT) will examine a case management program for 320 male and female patients suffering from coronary heart disease with multimorbidity in Mannheim, Germany. The main objectives are to evaluate how case management and social interaction alone compared to standard medical care affect the primary and secondary outcomes: physical health, quality of life, loneliness, depression, self-efficacy, outcome expectancies, social support, health locus of control, lifestyle behavior, social network, vulnerability, intention, severity, health worries and cognitive functions. Additionally, the secondary outcomes are studied as factors that mediate the effects of case management and social interaction alone compared to standard medical care on the primary outcomes. The trail consists of 3 treatment arms: 1) intensified case management; 2) social interaction alone 3) usual care. The intervention consists of a biweekly contact by trained case managers over the first 6-months and a monthly contact over the subsequent 6-months. Each contact involves an assessment of well-being, daily life, problems and offering emotional support and solutions or refer to the general practitioner if necessary (both intervention groups). For patients assigned to the "CM CHD" the contacts include medical control (like blood pressure or weight) and well-being as well as an additional core set of relevant outcome measures (e.g. need for treatment of fatigue). Patients assigned to the control group received usual care (no CM or contact). An additional fourth group is monitored. This group is consisting of patients who refused to take part in the study but gave consent to collect their practice data (not randomized). Each patient will be followed for 12 months. Extensive assessments and self-administered questionnaires take place at baseline, 6-month and 12-month for all patients in the three randomized groups.

Registry
clinicaltrials.gov
Start Date
July 2011
End Date
March 2013
Last Updated
13 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Genossenschaft Gesundheitsprojekt Mannheim e.G
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Diagnosed CHD
  • participation in the Disease Management Program (DMP) of CHD or
  • a risk score (Framingham or Procam) higher than 20%
  • two additional chronic diseases (multimorbid)

Exclusion Criteria

  • Patients living in institutionalized care
  • Patients having dementia
  • Patients associated with a life expectancy of less than one year
  • Patients who are not able to communicate in German language

Outcomes

Primary Outcomes

Change in health outcomes

Time Frame: Measured at baseline, 6 and 12 months follow-up

This includes biomarkers (blood pressure, BMI, weight, blood lipids), physical balance performance (semi tandem stand), care utilization and medication usage, clinical assessments and need for (medical) treatment (like dyspnea, fatigue, care, vomitus, thirst, lack of appetite, nausea, disorientation). Within the intervention group CM CHD weight and blood pressure is self-reported by patients biweekly within the first six months and monthly within the second six months.

Change in quality of life

Time Frame: Measured at baseline, 6 and 12 months follow-up

We will measure this variable using the "EQ-5D" and two additional items.

Secondary Outcomes

  • Change in Loneliness(Measured at baseline, 6 and 12 months follow-up)
  • Change in Depression(Measured at baseline, 6 and 12 months follow-up)
  • Change in self-efficacy(Measured at baseline, 6 and 12 months follow-up)
  • Change in social support(Measured at baseline, 6 and 12 months follow-up)
  • Change in health locus of control(Measured at baseline, 6 and 12 months follow-up)
  • Change in lifestyle behavior(Measured at baseline, 6 and 12 months follow-up)
  • Change in social network of family and friends(Measured at baseline, 6 and 12 months follow-up)
  • Change in outcome expectancies(Measured at baseline, 6 and 12 months follow-up)
  • Change in vulnerability(Measured at baseline, 6 and 12 months follow-up)
  • Change in intention(Measured at baseline, 6 and 12 months follow-up)
  • Change in severity(Measured at baseline, 6 and 12 months follow-up)
  • Change in health worries(Measured at baseline, 6 and 12 months follow-up)
  • Change in cognitive functions(Measured at baseline, 6 and 12 months follow-up)

Study Sites (1)

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