NCT06711575招募中不适用
Model-informed Individualized Treatment of Anti-Infective Drugs in Patients With Spinal Infections
Shandong University1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2024年10月12日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Clearance (L/h)
研究概览
简要总结
The purpose of this study is to describe the population pharmacokinetic characteristics in patients with suspected/confirmed spinal infections who are undergoing anti-infective drug therapy, and to evaluate effectiveness and safety of these drugs.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with suspected/confirmed spinal infections who are undergoing anti-infective drug therapy.
排除标准
- •Pregnant/lactating women.
- •There are other factors that the researchers think are not suitable for inclusion
结局指标
主要结局
Clearance (L/h)
时间窗: Through study completion, an average of 30 days
Volume of Distribution (L)
时间窗: Through study completion, an average of 30 days
次要结局
- the ratio of the area under the concentration-time curve from 0 to 24 hours(Through study completion, an average of 30 days)
- erythrocyte sedimentation rate(Through study completion, an average of 30 days)
- Adverse events(Through study completion, an average of 30 days)
研究者
Wei Zhao
Head of department of clinical pharmacy and pharmacology
Shandong University
研究点 (1)
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