Physician-initiated Medication Review in a Type 2 Diabetes Outpatient Clinic

Not Applicable

• Conditions: Polypharmacy
• Interventions: Other: Medication review; Other: Standard care

• Registration Number: NCT05501223
• Lead Sponsor: Bispebjerg Hospital

Brief Summary

Aiming to reduce polypharmacy in patients with type 2 diabetes by using physician-initiated medication reviews.

Detailed Description

Patients will be randomised to either standard care(annual visit at outpatient clinic) or standard care plus an intervention. The intervention is a medication consultation of 30-60 minutes that consist of a medication review and increased cross-sectoral communication. Follow-up is 6 months. Primary outcome are number of medications used, secondary outcomes are health related quality of life and persistance of medication changes.

Study Timeline

• Study Start: 2020-11-01
• Study First Submitted: 2021-08-03
• Status Verified: 2022-08
• Study First Submitted QC: 2022-08-12
• Last Update Submitted: 2022-08-12
• Study First Posted: 2022-08-15
• Last Update Posted: 2022-08-15
• Primary Completion: 2022-11
• Study Completion: 2022-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. DM2
2. 12 medications in the central prescription list

Exclusion Criteria

1. inability to give written consent (e.g., inability to understand the intervention or language barriers);
2. active cancer or palliative treatment;
3. admitted to the hospital.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intervention	Standard care	Standard care + medication review
Intervention	Medication review	Standard care + medication review
Control	Standard care	Standard care

Primary Outcome Measures

Name	Time	Method
Number of medications used at baseline compared to number of medications used at follow-up. Resulting in a rate of medications used at baseline compared to follow-up i.e. no. medication at follow-up/no. at baseline.	6 months	The no. of medications used at baseline will be compared to the no. of medications used at follow-up. This will result in a rate i.e. no. at follow-up/no. at baseline which can be compared between groups resulting in a rate ratio. Medication usage is determined by number of medications listed in the central prescription list.

Secondary Outcome Measures

Name	Time	Method
EQ5D index score. (a Euro Quality of Life 5-dimension 5-level (EQ-5D-5L) scale). The score is retrieved by using the validated EQ5D questionnaire which translates to a corresponding EQ5D index score using country specific value sets.	6 months	Health related quality of life measured by EQ5D index score using Danish value sets (ranging from -0.7 (worst quality of life) to 1 (best quality of life)).

Trial Locations

Locations (1)

Bispebjerg Hospital; 🇩🇰 Copenhagen, Denmark