IRCT20200419047128N1已完成2 期
Assessment of the effect of Tranilast (novel NLRP3 Inflammasome inhibitor ) on the efficacy of antiviral drug regimens in the treatment of patients with severe COVID19
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 85 years（—）
- 性别
- All
入选标准
- •Age =18 years
- •Laboratory polymerase chain reaction (PCR) confirmed infection with COVID19
- •Lung involvement confirmed with chest imaging Hospitalized with: Fever Or Cough Less than 8 days since illness onset
- •Willingness of study participant to accept randomization to any assigned treatment arm
- •Acceptance of non-participation in another study before the 28th day of the study
- •arterial blood O2 saturation under 93%
- •non-pregnant females
排除标准
- •Autoimmune diseases (lupus, MS, etc.)
- •Hepatic failure
- •Hepatit B, C,
- •pregnant and lactating women
- •use of antioxidants, anti-inflammatory and immunosuppressant drugs
- •kidney failure
- •known allergy to Tranilast
研究者
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