Lyon Prosthetic Joint Infection Retrospective Cohort Study
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Hospices Civils de Lyon
- Enrollment
- 400
- Locations
- 1
- Primary Endpoint
- Description of type of prosthesis PJI
Study Overview
Brief Summary
Bone and joint infections (BJI), although infrequent (prevalence of 70 per 100,000 in France), have a significant economic and clinical impact. Between 2008 and 2013, the prevalence of BJI increased and infections involving joint prosthesis (PJI) represent a third of BJI in France. They are most often post-operative and more expensive than native IOAs.
This study aims to describe PJI and understand the failure mechanisms of PJI in order to improve their management.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •patients having had a PJI between 2018 and 2020
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Description of type of prosthesis PJI
Time Frame: between 2018 and 2020
number of prosthesis
Description of patients having had a PJI
Time Frame: between 2018 and 2020
type of patients: age
description of antibiotic treatment
Time Frame: between 2018 and 2020
duration of antibiotic treatment
rate of PJI
Time Frame: between 2018 and 2020
proportion of PJI among all BJI
Description of PJI
Time Frame: between 2018 and 2020
acute/chronic
description of antibiotic used
Time Frame: between 2018 and 2020
type of antibiotic : name
description of surgical treatment
Time Frame: between 2018 and 2020
type of surgery: 1-step exchange, 2- step exchange, DAIR
Description of comorbidities of patients having had a PJI
Time Frame: between 2018 and 2020
type of comorbidities..
rate of bacteria
Time Frame: between 2018 and 2020
epidemiologic description of PJI
Secondary Outcomes
- rate of failure(between 2018 and 2020)
- description of the failure(between 2018 and 2020)