Analysis of prevalence of corneal biomechanical changes post squint study in age group of 12-40 years

Title :  Analysis of prevalence of corneal biochemical changes in post squint surgeries in patients with age group of 12-40 years.

Squint, also called crossed eyes, is a condition where the two eyes do not point in the same direction. This can affect a person’s appearance, confidence, and sometimes even their ability to see clearly with both eyes together. Surgery to correct squint is commonly done in both children and adults to improve eye alignment, vision, and quality of life.

The front part of the eye, called the cornea, is like the clear window through which we see. It not only lets light into the eye but also has to stay strong and maintain its shape for clear vision. Now we have advanced tools like the Corvis ST, which use a gentle puff of air and a special camera to measure how flexible or strong the cornea is. These measurements can tell us if surgery affects the eye’s structure and whether those effects are temporary or long-lasting.

Study Purpose:

This is a prospective cohort study will be conducted from August 2025 to July 2026,enrolling 42 patients with squint .

This study will check if squint surgery causes any changes in the strength or flexibility of the eye in people aged 12 to 40 years. We will use the Corvis ST machine to measure these changes before surgery, and again at 1 month and 3 months after surgery.

We will record information about each patient and measure the eye’s strength before surgery.

Perform squint surgery using standard procedures.

Repeat the eye strength test at 1 month and 3 months after surgery.

Compare results based on the type of surgery, number of muscles operated, and type of incision used.

The Primary Objective is to check if squint surgery causes any changes in the strength and flexibility of the front part of the eye (cornea) using the Corvis ST machine before surgery, and again at 1 month and 3 months after surgery

While Secondary Objectives are -To compare changes based on the type of surgery

-To see if changes differ when one or more muscles are operated.

-To check if the type of cut made during surgery (limbal vs forniceal) affects the results.

-To find out whether the changes are temporary or long-term.

-To see if changes in the cornea relate to any changes in eyesight after surgery.

Expected results-

We expect to find temporary changes in corneal strength and flexibility after surgery that should return close to normal within 3 months.

Or does type of surgery or incision or number of muscles operated has any effects on outcome of surgery- in turn on postoperative vision.