A Clinical trial to study the effect of an Ayurvedic Drug Shothankusha Ras in the patients with Chronic Kidney Disease

Phase 2

Not yet recruiting

• Conditions: Chronic Kidney Disease

• Registration Number: CTRI/2017/03/008118
• Lead Sponsor: Dr Ratna Priyadarsini y

Brief Summary

A clinical trial is done to  evaluate the efficacy of the Ayurvedic preparation Shothamkusha Ras in the mangement of Kaphaja Shotha vis - a- vis Chronic Kidney Disease and to validate scientifically the observations  that would significantly improve the Renal Function. Shothamkusha Ras, a unique formula  of Herbo- Minerals which has its reference from an authentic Ayurvedic Classical text Bhaishjya Ratnavali and  is given Orally , 125 mg, twice a day  for 60 days. The study would be conducted in India aimed to complete in 4 years and the trial time being 18 months. Primary outcome measures will be relief in signs and symptoms (Subjective Parameters)  number of patients with sustained reduction in abnormal Kidney function tests to 50% of baseline , arrest of the progress of the disease into ESRD and prevention of Dialysis and Renal Transplant.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2017-08-03
• Study Start: 2018-01-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1.Diagnosed cases of CKD of stage I,II,III 2.Elevated Serum Creatinine levels 3.Elevated Blood urea levels 4.Chronic Glomerular Nephritis 5.Nephritic Syndrome.

Exclusion Criteria

1.Obstructive Causes 2.Urinary Calculi 3.Enlarged prostrate 4.Multiple Myeloma 5.Vesico Urethral Reflux 6.Clinically Non Responding Cases.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Relief in signs and symptoms and arrest of progress of Chronic Kidney Disease with sustained reduction in abnormal kidney function tests to 50% baseline	Relief in signs and symptoms expected in 60 days

Secondary Outcome Measures

Name	Time	Method
Change in abnormal Serum Creatinine levels and Blood Urea Nitrogen and Parenchymal changes in Kidney through Ultrasonography

Trial Locations

Locations (1)

Dr NRS Govt Ayurvedic College; 🇮🇳 Krishna, ANDHRA PRADESH, India

Dr NRS Govt Ayurvedic College

🇮🇳Krishna, ANDHRA PRADESH, India

Ratna Priyadarsini Y

Principal investigator

9440353825

dr.ratnapriyadarsini@gmail.com