NCT07316439进行中（未招募）不适用
Clinical Outcomes of ER-Positive to Negative Conversion Versus Triple-Negative Breast Cancer (TNBC): Evidence From a 18F-fluoroestradiol Positron Emission Tomography/Computed Tomography (18F-FES PET/CT) Guided Propensity-Score-Matched Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 197
- 试验地点
- 1
- 主要终点
- Progression-Free Survival
研究概览
简要总结
This study aimed to compare survival outcomes and clinical characteristics between ER loss and metastatic triple-negative breast cancer (mTNBC) patients, exploring the prognostic implications of dynamic ER changes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed with breast cancer (according to International Classification of Diseases 10th Revision) with confirmed metastasis, regardless of being de novo diagnosed or progressed from a non-metastatic stage.
- •MBC patients who underwent 18F-FES PET/CT at the Fudan University Shanghai Cancer Center between 2017 and 2023
- •Patients diagnosed with primary ER-positive tumor and who were yet to receive any systemic therapy during the advanced stage
- •Contemporaneous patients with metastatic TNBC at initial diagnosis
排除标准
- •Patients with incomplete medical records and those diagnosed with secondary primary tumors
结局指标
主要结局
Progression-Free Survival
时间窗: 6 weeks
次要结局
- Overall Response Rate(6 weeks)
- Disease Control Rate(6 weeks)
研究者
研究点 (1)
Loading locations...
相似试验
Enrolling By Invitation
不适用
Survival Analysis of Surgical Resection Versus Observation in Patients With Initially uHCC Achieving CR After Systemic TherapyHepatocellular CarcinomaNCT07290764Fujian Provincial Hospital729
招募中
2 期
Phase II multicentric study: efficacy evaluation of neo-adjuvant treatment associated with maintenance therapy by anti-PD1 immunotherapy on disease-free-survival (DFS) in patients with resectable mucosal melanoma2024-513027-16-00Institut Gustave Roussy60
招募中
不适用
Real-world Outcomes of Peripheral T-cell Lymphoma: A Multicenter Retrospective and Prospective Cohort StudyNCT07270861Fudan University3,000
招募中
3 期
Comparing two treatment regimen for sinuses tumors and salivary glands: radiotherapy versus chemoradiotherapy2024-513972-16-00Groupe Oncologie Radiotherapie Tete Cou342
招募中
1 期
Phase I/II Clinical Study of JMT108 Injection for the Treatment of Advanced Malignant Melanoma and Urinary Tract TumorsUnresectable Locally Advanced or Metastatic Urinary Tract TumorsNCT07280832Shanghai JMT-Bio Inc.500